Promising Future, LLC

Promising Furture, LLC

Carol A Kruse

Richard Tritz

Provided in certain embodiments are methods for pairing patient cells and donor cells to prepare cytotoxic T cells, either in vitro or, when their formation is induced in a subject, in vivo. Such cytotoxic T cells could be administered to the patient for treating certain disorders, such as a cancer (for example, brain cancer).

Pairing processes for preparing reactive cytotoxic T cells

Provided herein are compositions and methods of preparing therapeutic cytotoxic T cells. In certain embodiments, such T cells are generated through activation of donor cells by patient stimulator cells.

Compositions and methods of preparing alloreactive cytotoxic T cells

Provided in certain embodiments are methods for pairing patient cells and donor cells to prepare cytotoxic T cells. Such cytotoxic T cells could be administered to the patient for treating certain disorders, such as a cancer (for example, brain cancer).

Pairing processes for preparing alloreactive cytotoxic T cells

Provided herein are methods and compositions for killing tumor cells. In certain embodiments, compositions can promote apoptosis by down-regulating FAPP2 and PATZ1 products.

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San Diego, CA, United States of America

Carol A Kruse