Amo Groningen B.v.

Amo Wavefront Sciences, LLC

Abbott Medical Optics Inc.

Amo Development, LLC

Johnson & Johnson Surgical Vision, Inc.

Carmen Canovas Vidal

Hendrik Albert Weeber

Robert Rosen

Marrie H Van Der Mooren

Patricia Ann Piers

Aixa Alarcon Heredia

Franck Emmanuel Gounou

Dora Sellitri

Mihai State

Robert Rosén

Daniel Ralph Neal

Thomas Daniel Raymond

Richard James Copland

Stephen W Farrer

Daniel Richard Hamrick

Wei Xiong

Paul D Pulaski

Sieger Meijer

Hendrik A Weeber

Pablo Artal

Luuk Franssen

Kaccie Y Li

Marrie Van Der Mooren

Huawei Zhao

Theophilus Bogaert

Richard Hartman

Robin Zonneveld

Sverker Norrby

Henk A Weeber

Miguel Faria Ribeiro

Bram Koopman

Roy Reints

Yichao Liu

Ariel Zenouda

Paul Pulaski

Bart Cannegieter

Christopher Reeves

Franck Gounou

Patricia A Piers

Robert ROSÉN

Systems and methods are provided for improving overall vision in patients suffering from a loss of vision in a portion of the retina (e.g., loss of central vision) by providing symmetric or asymmetric optic with aspheric surface which redirects and/or focuses light incident on the eye at oblique angles onto a peripheral retinal location. The intraocular lens can include a redirection element (e.g., a prism, a diffractive element, or an optical component with a decentered GRIN profile) configured to direct incident light along a deflected optical axis and to focus an image at a location on the peripheral retina. Optical properties of the intraocular lens can be configured to improve or reduce peripheral errors at the location on the peripheral retina. One or more surfaces of the intraocular lens can be a toric surface, a higher order aspheric surface, an aspheric Zernike surface or a Biconic Zernike surface to reduce optical errors in an image produced at a peripheral retinal location by light incident at oblique angles.

Intraocular lens that improves overall vision where there is a local loss of retinal function

Intraocular lenses for reducing negative dysphotpsia (ND) are described herein. An example ophthalmic lens can include an optic () with a central optical zone () disposed about the optical axis (OA) and an attenuation optical zone () disposed about the central optical zone (), wherein the attenuation optical zone () is contiguous with the central optical zone (), and wherein optical power of the ophthalmic lens is gradually reduced within the attenuation optical zone ().

Intraocular lenses for reducing negative dysphotopsia

Apparatuses, systems and methods for providing improved ophthalmic lenses, particularly intraocular lenses (IOLs), include features for providing improved extended depth of focus lenses. Exemplary ophthalmic lenses can include an optic including a diffractive profile including at least one set of echelettes, each echelette of the set having a different width in r-squared space than any other echelette of the set and the at least one set of echelettes repeating at least once upon the optic.

Achromatic lenses and lenses having diffractive profiles with irregular width for vision treatment

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining at least one photic phenomenon experienced by the subject after implantation of the IOL; and applying a plurality of laser pulses to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, a phase shift in the IOL to compensate for the photic phenomenon.

Systems and methods for correcting photic phenomenon from an intraocular lens and using refractive index writing

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes vergence matching for an intraocular lens (IOL) having an optical profile induced by refractive index writing.

Systems and methods for vergence matching with an optical profile and using refractive index writing

A method of quantifying the effect of peripheral optical errors on patient locomotion includes projecting a pattern on the floor that includes a discrete shapes and empty spaces between the discrete shapes. The method also includes tracking a position of the participant along the pattern as the participant traverses the pattern, and determining foot placement accuracy, utilizing a optical motion capture system and a computer, as the participant walked through the pattern by determining a total area of overlap between the participant's feet and the empty spaces of the pattern. In another embodiment, the method includes arranging obstacles in front of a participant, intermittently displaying a character in front of the participant, determining participant's accuracy in identifying or counting the characters, and determining the participant's step length and foot clearance as the participant steps over the obstacles to quantify the effect of the peripheral optical errors on the participant's locomotion.

System and method for determining the impact of peripheral optical errors on patient locomotion

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining a deviation in position of at least one optical element from a reference line corresponding to alignment of the apex of the cornea, center of the pupil, center of the IOL, and fovea, and/or determining a tilt of at least one of the optical elements relative to the reference line. The method can further include applying a plurality of focused laser pulses to a selected area of the implanted IOL to produce, through refractive index writing, a phase change pattern on the IOL that is configured to compensate for the deviation(s) and/or tilt to improve the foveal vision of the subject.

Systems and methods for improving vision from an intraocular lens in an incorrect position and using refractive index writing

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method of treating an ocular disease of a subject having an implanted intraocular lens (IOL) includes determining visual needs of a subject that are associated with an ocular disease of the subject determining a pattern of a plurality of pulses of radiation to apply, by refractive index writing, and applying the plurality of pulses of radiation to the one or more selected areas of the IOL.

Systems and methods for treating ocular disease with an intraocular lens and refractive index writing

Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects. The combination can provide an increased depth of focus that is greater than an individual depth of focus of either the refractive profile or the diffractive profile.

Progressive power intraocular lens, and methods of use and manufacture

Apparatuses, systems, and methods for providing improved intraocular lenses (IOLs) and other refractive treatment modalities involve fabricating the IOL or developing the treatment based on a refractive profile. Exemplary techniques include obtaining a base wavefront power profile corresponding to a theoretical lens, adding a second wavefront profile defined by the combination of one or more zones described by a cosine function to obtain a final wavefront power profile, determining a refractive profile based on the final wavefront power profile, and fabricating the intraocular lens or determining the treatment based on the refractive profile.

Refractive extended depth of focus intraocular lens, and methods of use and manufacture

A psychophysical method, system, and apparatuses to characterize visual symptoms. A method may include presenting one or more stimuli to a patient indicating one or more visual symptoms. The patient may produce one or more responses to the stimuli. A determination of a measure of visual symptoms of the patient may be made utilizing a Bayesian method based on the responses.

Psychophysical method to characterize visual symptoms

Systems and methods for evaluating ND are described herein. An example method can include constructing a non-sequential (NSC) ray-tracing model of an eye with an ophthalmic lens, and modelling a light source and a detector. The detector can be configured to mimic a retina of the eye. The method can also include computing irradiance data using the light source, the NSC ray-tracing model, and the detector. Irradiance data can be computed for each of a plurality of pupil sizes. The method can further include evaluating ND by analyzing the respective irradiance data for each of the pupil sizes. Also described herein are methods for designing an ophthalmic lens edge that reduces the incidence of ND for a given ophthalmic lens by adjusting the edge thickness and/or the scatter.

Systems and methods for evaluating and reducing negative dysphotopsia

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining at least one modification to be made to an IOL implanted in a subject to improve the vision of the subject, wherein the IOL has a first index of refraction; and based on the determination, applying laser radiation to at least one selected area of the IOL to form, within the IOL, at least one additional layer having a different index of refraction than the first index of refraction and a particular shape within the IOL configured to improve the vision of the subject.

Systems and methods for multiple layer intraocular lens and using refractive index writing

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Groningen, Netherlands

Carmen Canovas Vidal