Flagship Pioneering Innovations Vi, LLC

Carlos Sanchez

Barrett Ethan Steinberg

Anne Helen Bothmer

Ananya Ray

Robert Charles Altshuler

Cecilia Giovanna Silvia Cotta-Ramusino

Randi Michelle Kotlar

Nathaniel Roquet

Robert James Citorik

William Edward Salomon

Kyusik Kim

William Querbes

Luciano Henrique Apponi

Daniel Raymond Chee

Aamir Mir

Gregory David McAllister

Zhan Wang

The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating cystic fibrosis, e.g., in subjects having a mutation resulting in F508del, are described.

CFTR-modulating compositions and methods

The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject.

Methods and compositions for modulating a genome

Growing community of inventors

Boston, MA, United States of America

Carlos Sanchez