Grifols Worldwide Operations Limited

Grifols Engineering, S.a.

Carlos Roura Salietti

Jordi Boira Bonhora

Daniel Fleta Coit

Carlos Roura Fernandez

David Pages Becerra

Jose Coca Garrote

Antonio Manuel Paez Regadera

A system for dispensing a liquid in a closed chamber includes at least one rapid transfer port in at least one wall of the closed chamber. In addition, a liquid is dispensed in a closed chamber that includes at least one rapid transfer port in at least one wall of the closed chamber.

System and method for dispensing a liquid in a closed chamber

A system for the sterile filling of containers for pharmaceutical products, which includes a device for sterilizing containers and a machine for filling sterilized containers, wherein the device for sterilizing containers includes at least one autoclave, and wherein the system includes an automated container-accumulation device and means for automatically transporting the containers sterilized in the autoclave from said autoclave to the container-filling machine via said container-accumulation device.

System and method for the sterile filling of containers

A device for therapeutic plasma exchange includes an extracorporeal circuit, which includes a blood supply line, a separating unit, a line for infusion of formed elements, a line for infusion of replacement fluid, a blood plasma line, an anticoagulant line and at least one independent line for therapeutic drugs. The independent line can include a storage for the therapeutic drug, a conveyer of therapeutic drug, a propelling device and a controller configured to control flow of the therapeutic drug.

Device for therapeutic plasma exchange

An device is for electron-beam irradiation sterilization of flexible bags that may contain human plasma protein solutions for therapeutic use. The device has two electron accelerators, a first accelerator emitting an electron beam with energies between 400 and 500 keV and a second accelerator emitting an electron beam with an energy of at least 4 MeV. A sterilization method by electron-beam irradiation provides sterilization of such flexible bags. An in-line filling process for flexible bags can use the sterilization device and method.

Device and method for sterilizing flexible bags by electron beam irradiation

A sterilization method includes irradiating flexible bags, in particular, bags of the type that can contain solutions of human plasma proteins for therapeutic use. The sterilization method includes electron beam irradiation. An in-line method for filling flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use can use the sterilization method.

Method for sterilizing flexible bags

A container for sterilizing flexible bags can be for pharmaceutical use. The container includes an upper flat structure including at least one element supporting the flexible bags and designed to accommodate a plug port of the flexible bag. The support element includes at least one fastening element, which is suitable for retaining the flexible bags once they are inserted into the support element. The container also includes a lower receptacle designed to contain the upper flat structure and to couple to the upper flat structure in a detachable manner. The container further includes a cap for hermetically sealing the lower receptacle.

Container for sterilizing flexible bags

A device is for sterilization by electron beam irradiation of flexible bags, in particular flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use. A sterilization method includes irradiating flexible bags by electron beam irradiation. An in-line method for filling flexible can use the sterilization device and method.

Device for sterilization of flexible bags and method for sterilizing flexible bags

A method and device detect defects in the closure of encapsulated vials. The method includes scanning a profile of the capsule and of the vial using a profilometer, thus obtaining a point cloud. From the point cloud obtained, calculating at least one of the following parameters: diameter or radius of the closure circumference of the capsule; angle of intersection between the lower skirt and the side of the capsule; length of the lower skirt; and/or a distance from the end of the lower skirt to the neck of the vial. The method determines whether any of the parameters calculated in the previous step exceeds a predetermined value. The device detecting defects in the closure of encapsulated vials includes a profilometer configured to scan a profile of the capsule and of the vial and a control device configured to execute the method.

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Arenys de Munt, Spain

Carlos Roura Salietti