Coulter Corporation

Coulter International Corp.

Coulter Electronics, Inc.

Florida Power & Light Company

Pricewaterhousecoopers Llp

Carlos M Rodriguez

Wallace H Coulter

Thomas R Russell

Ronald D Paul

Kenneth H Kortright

Constance M Hajek

James Carey Hudson

Stephen L Ledis

Mark A Wells

John D Hollinger

James L Wyatt

Kristie M Gordon

Raymond E Garwood

Nicholas F Santoro

Brian Jones

Olavi Siiman

Alexander Burshteyn

John A Maples

Robert Cary Leif

Jose M Cano

Chiranjit Deka

Michael R Groves

Allan F Horton

David Clarke

Robert Stewart Frank

Barbara Carrillo

Carlos Reyes

James Keller Whitesell

Cydney Aiken

William A Fiorentino

Bob Gruman

Weiyan Gong

Pradeep Giri

Thomas Joseph Puthiyamadam

Jonpol Lavalle

Kryssie Knowles

Federico Loguzzo

Warren Barton

Richard Longman

This invention relates to software adoption platform systems and methods. An exemplary computer-implemented method comprises at an electronic device with a display, displaying a window associated with a software system; displaying, within the window, a user interface corresponding to a software adoption platform, wherein the user interface corresponding to the software adoption platform comprises: a user-specific score associated with the software system, and a plurality of user affordances corresponding to a plurality of actions within the software system; upon selection of a user affordance of the plurality of user affordances, automatically displaying a page of the software system in the window based on the selected user affordance, and automatically displaying one or more messages overlaid over the page of the software system, wherein the one or more messages are generated by the software adoption platform.

Enterprise software adoption platform systems and methods

In accordance with one embodiment, an adapter for connecting a network device is provided. The adapter includes adapter housing. The adapter housing further includes a base and a wall, such that the wall extends axially from the base. The base of the adapter housing also includes an inner surface and an outer surface. The adapter includes a plurality of socket openings that extend across the base between the inner surface and the outer surface. The plurality of socket openings extend axially, the socket openings continue across the inner surface of the base through the first end of the rim and the second end of the rim. In one embodiment, the adapter includes a bypass circuit. The bypass circuit allows a network device to get power from a line side of a power meter and the consumer to get power from the load side of the power meter.

Systems and methods for a power adapter

A method for performing screening of one or more cell groups of interest obscured by a cell population such as one or more subsets of interest of a WBC population utilizing at least one light sensing parameter. The cell group of interest is enumerated by utilizing microspheres having monoclonal antibodies bound thereto to modify the sensed characteristics of specified cells to differentiate the cell group of interest from the obscuring cell population.

Method and apparatus for screening microscopic cells utilizing light scatter techniques

A method and apparatus for differentiating and enumerating the five major sub-populations of leukocytes in a blood sample (i.e., lymphocytes, monocytes, eosinophils, neutrophils and basophils) uses multiangle light scatter and DC (Coulter) volume measurements. Light scattering characteristics of the leukocytes are determined within five different angular ranges, all being lower than 40 degrees. The invention is particularly useful in differentiating and enumerating the basophil sub-population which has heretofore required more complex apparatus and/or chemical processing.

Method and apparatus for differentiating and enumerating leukocytes

A blood analyzing instrument includes a single transducer for simultaneously measuring the DC volume, RF conductivity, light scattering and fluorescence characteristics of blood cells passing through a cell-interrogation zone. Preferably, the transducer includes an electro-optical flow cell which defines a cell-interrogation zone having a square transverse cross-section measuring approximately 50&times;50 microns, and having a length, measured in the direction of cell flow, of approximately 65 microns.

Method and apparatus for analyzing cells in a whole blood sample

A method and apparatus for performing screening of obscured or partially obscured cells to enumerate one or more cell population subsets. For example, a whole blood sample or portion thereof is screened to provide the desired analysis of one or more white blood cell population subsets in the sample. A white blood cell population including the obscured subset of interest is first counted, along with a standard population. The standard population can be one of the total number of white blood cell populations, a second white blood cell population which does not obscure the shifted or non-shifted sensed characteristic of the subset of interest, an artificial population formed by microspheres which also do not obscure the shifted or non-shifted sensed characteristic of the subset of interest or a white blood cell population into which the sensed characteristic of the subset will be wholly or partially shifted. The sensed characteristic of the white blood cell population subset of interest then is shifted by binding microspheres having monoclonal antibodies specific to the white blood cell population subset of interest to the cell population. The white blood cell population, and the standard population then are again counted and compared to the original counts to obtain an enumeration of the white blood cell population subset of interest.

Method and apparatus for screening obscured or partially obscured cells

A stable colloidal particle comprises a colloidal-sized core substrate having amine-reactive functional groups thereon with an aminodextran coating over its peripheral surface and a layer of colloidal-sized metallic solid overlaying the aminodextran coating. A linker comprising aminotrithiolate attached to the metallic solid has a free amino group to which a protein is attached by covalent bonding to the free amino group. Such novel particles are useful in flow cytometry, particularly useful in the simultaneous analyses of subpopulations of leukocytes. Methods of preparation of such particles, as well as methods of use are provided. These conjugates enable the simultaneous analyses of at least two different mutually exclusive subsets of white blood cells, based on the binding affinity of the conjugated protein.

Protein-colloidal metal-aminodextran coated particle and methods of

The present invention provides an apparatus and method to determine individual red blood cell shape within a flow cytometric aperture. Cell shape is determined by measuring the asymmetry of a light scatter pattern produced by laser illumination of the cell within the aperture by light scatter detectors which collect light from specific angular regions of light scatter, and analyzing the asymmetry of the light scatter patters to determine the individual red blood cell shape. Embodiments of the invention further provide for the determination of red blood cell shape by measuring the asymmetry of a light scatter pattern and measuring electrical resistance of the red blood cell.

Apparatus and method for determination of individual red blood cell shape

A reticulocyte analyzing method and apparatus in which a biological sample stream of ghosted red cells is passed into and through a point focused beam of light, such as laser light. A light detector structure is positioned with respect to the axis of the light beam to provide a light output pulse indicative of the passage of each cell. Electrically conductive contacts within the fluid stream can provide additional electrical pulse outputs of each cell. A staining reagent can be utilized with a ghosting reagent to further differentiate the reticulocytes. The light and the light and electronic produced output pulses or signals can be combined to define and quantify reticulocytes as distinct from other known cell types.

Reticulocyte analyzing method and apparatus utilizing light scatter

A method and apparatus for accelerating at least one definitive biological reaction including increasing the accuracy of determinations made therefrom. The reaction involves selected viable biological cells which are prepared in a small sample volume and rapidly mixed with microspheres having antibody specific at least to specific ones of the cells bound thereto. The microspheres can be magnetic and the bound cells can be magnetically removed to analyze the remaining blood cell populations. The microspheres can be introduced sequentially or simultaneously.

Method and apparatus for rapid mixing of small volumes for enhancing

A method and apparatus for automatically and rapidly, retrieving, counting and/or analyzing at least one selected white blood cell population and/or subset thereof of a whole blood sample or portion thereof. A volume of a biological sample containing the white blood cells is prepared and at least one reactant specific or preferential at least to some selected biological cells is introduced thereto and rapidly mixed for a short period of time. The opacity and/or volume parameter of the cells can be modified and the mixture is then counted and analyzed in one or more steps to obtain the desired white blood cell population analysis. The biological sample can be a whole blood sample and the reactant can include or be a lyse or a monoclonal antibody bound to microspheres, which will bind to specific ones of the cells or a combination of lyse and microspheres with antibody bound thereto. The microspheres can be magnetic and the bound cells can be magnetically removed for retrieving and analyzing the remaining blood cell population.

Automated analyzer for screening cells or formed bodies for enumeration

A method and apparatus for automatically and rapidly, retrieving counting and/or analyzing at least one selected population of cells or formed bodies, such as a white blood cell population and at least one subset thereof of a whole blood sample or portion thereof. A volume of a biological medium containing the white blood cells is prepared and at least one reactant specific or preferential at least to some selected biological cells is introduced thereto and rapidly mixed for a short period of time. A multipart blood cell analysis is obtained with a single sensing parameter by depleting at least one WBC subset population. The percentage of a desired WBC population subset or the overlapping of WBC subset populations also can be obtained by subtracting one or more obscuring WBC subset populations. The biological sample can be a whole blood sample and the reactant can include or be a lyse or a monoclonal antibody bound to microspheres, which will bind to specific ones of the cells or a combination of lyse and microspheres with antibody bound thereto. The microspheres can be magnetic and the bound cells can be magnetically removed for retrieving and analyzing the remaining blood cell population.

Method and apparatus for screening cells or formed bodies with

Growing community of inventors

Miami, FL, United States of America

Carlos M Rodriguez