Yeda Research and Develpment & Co. Ltd

Carlos Gitler

Michel Revel

David Mirelman

Marion Huber

Leonard I Garfinkel

Shmuel Rozenblatt

Michael Giladi

Itzhak Yuli

Biosensors for qualitative and quantitative analysis comprise an amphipathic liquid crystalline membrane composed of a lipid bilayer attached to a recording electrode via bridging anchoring molecules. The lipid bilayer is doped with biologic or synthetic ion channels and is in continuous contact with a bulk aqueous medium on both its surfaces. The bridging anchoring molecules may contain a phospholipid moiety linked to a polyoxylakylene chain terminated with a thiol or thioether residue.

Biosensors including lipid bilayer doped with ion channels anchored to a

An assay for the determination of the presence or absence of E. histolytica and for differentiation of these from other types of amoebae, as well as for the determination of whether the E. histolytica belongs to a symptomatic or asymptomatic strain, is carried out by means of a DNA-probe adapted to selectively hybridize only to the DNA of the amoeba tested. The probes being used selectively hybridize with, and thus diagnose the presence of, symptomatic (pathogenic) and asymptomatic (non-pathogenic) strains, respectively.

Assay for amoebae and probes for use therein

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Rehovot, Israel

Carlos Gitler