Novagenit S.r.l.

Mero S.r.l.

Bonalive Biomaterials Oy

4i S.r.l.

Carlo Luca Romano

Giovanna Pitarresi

Gaetano Giammona

Fabio Salvatore Palumbo

Lorenzo Drago

Edgardo Cremascoli

Fredrik Ollila

Enzo Meani

Tommaso Brenicci

Marco Bertoni

Jimmy Lucchesi

The present invention relates to an implantable paste comprising bioactive glass powder having a size distribution of 0.5-45 μm, bioactive glass granules having a size distribution between 100 and 4000 μm, low molecular weight polyethylene glycol having a molecular weight range of 200-700 g/mol, medium molecular weight polyethylene glycol having a molecular weight range of 700-2500 g/mol, high molecular weight polyethylene glycol having a molecular weight range of 2500-8000 g/mol and glycerol. The composition of the bioactive glass is 45-55 weight-% of SiO, 20-25 weight-% of NaO, 18-25 weight-% of CaO and 3-6 weight-% of PO, and the molecular weight of the low molecular weight polyethylene glycol and of the medium molecular weight polyethylene glycol differ from each other by at least 80 g/mol and that the molecular weight of the medium molecular weight polyethylene glycol and of the high molecular weight polyethylene glycol differ from each other by at least 300 g/mol.

Implantable paste and its use

The present invention concerns a sterile closed loop device for medical-surgical use intended for the collection, the transportation and the processing of prostheses and/or biological samples and the like, having at least one collection compartment provided with an hermetically closable main opening, for the introduction of said prosthesis and/or biological samples and the like to be analyzed, so as to be contained in it, at least one containment chamber, in which a solution is contained for the chemical detachment of bacteria adhering to animate or inanimate surfaces, such as prostheses and the like, and/or bacterial biofilm, said containment chamber being selectively communicating with said collection compartment, so that said solution can be conveyed from said containment chamber to said collection compartment, for the chemical separation of bacteria to said prosthesis and/or biological samples and the like to be analyzed, that can be inserted in said collection compartment, and extraction means of said solution for the chemical detachment of bacteria from said collection compartment. The present invention also concerns a method for collecting, transporting and processing a prosthesis and/or biological samples and the like to be analyzed.

Closed circuit sterile device and method of collection, transport and processing in total sterile chain

The present invention relates to hydrogels endowed with antibacterial properties, to be used for injection in damaged bones or in the production of antibacterial coatings of prostheses for implant in the human or animal body, obtained by loading with antibacterial agents hydrogels formed by derivatives of hyaluronic acid; the invention also relates to a kit of parts for producing the antibacterial hydrogels.

Antibacterial hydrogel and use thereof in orthopedics

Growing community of inventors

Milan, Italy

Carlo Luca Romano