Invatec S.p.a

Medtronic Vascular, Inc.

Corcym S.r.l.

Carlo Guala

Massimo Morero

Claudio Silvestro

Jeffery C Argentine

Francesco Piccagli

Darren Galligan

Giovanni Scalvini

Kieran Coghlan

Marina Strasly

Francesco Valle

Luca Copeta

Claudia Vimercati

Davide Zanetti

Marco Miliani

Michele Saputo

Ludwig Compagnoni

Giampiero Nicoli

A prosthetic assembly for repairing a target tissue defect within a target vessel region configured includes an exclusion structure sized to substantially bypass target tissue defect, and includes a branch assembly. The branch assembly can include a self-expanding outer branch prosthesis having an inflow region configured to deform to a non-circular cross-sectional-shape when deployed, and a support structure at least partially disposed within the inflow region. The support structure preserves blood flow to the branch vessel while the deformed inflow region inhibits blood leakage between and/or around the prosthetic assembly.

Endoluminal prosthetic assemblies, and associated systems and methods for percutaneous repair of a vascular tissue defect

An occlusion bypassing apparatus is disclosed for re-entering the true lumen of a vessel after subintimally bypassing an occlusion in a vessel. The apparatus includes an outer shaft component, an inner shaft component disposed within the outer shaft component, and a needle component slidably disposed within the inner shaft component. The inner shaft component includes a body portion and a needle housing, which is distal to the body portion. The needle housing is less flexible than the body portion. In order to smooth the transition between the body portion and the needle housing, the needle housing includes a transition portion that has a variable flexibility along its length that decreases in a distal direction. A curved distal end of the needle component is distally advanced relative to the inner shaft component to pierce through the intima of the vessel and thereafter enter the true lumen.

Occlusion bypassing apparatus with varying flexibility and methods for bypassing an occlusion in a blood vessel

An occlusion bypassing apparatus for re-entering the true lumen of a vessel after subintimally bypassing an occlusion in a vessel. The apparatus includes an outer shaft component, a needle component, and an inflatable balloon. The outer shaft component has a side port proximal to a distal end thereof and a needle lumen there-through that includes a curved distal portion that terminates at the side port of the outer shaft component. The needle component is configured to be slidably disposed within the needle lumen of the outer shaft component. The inflatable balloon includes a body portion that is disposed distal to the side port of the outer shaft component, and the body portion of the balloon has a flattened profile in an inflated state with first and second chambers that laterally extend from opposing sides of the outer shaft component for stabilizing the apparatus within a subintimal space.

Occlusion bypassing apparatus with a re-entry needle and a distal stabilization balloon

Catheter devices and methods useable for directing a guidewire from a subintimal position within the wall of an artery into the true lumen of that artery or other applications wherein it is desired to direct a guidewire or other elongate device from one location to another location within a subject's body.

Re-entry catheters and related methods

Catheters, systems, and methods for achieving renal neuromodulation by intravascular access. A catheter has an energy delivery device positionable in a renal blood vessel and being transformable between a radially constrained low-profile state and a self-expanded deployed state. The energy delivery device includes a first electrode array spaced longitudinally from and flexibly connected to a second electrode array, the arrays being sized and shaped so that the electrode regions contact an interior wall of the renal blood vessel when the energy delivery device is in the deployed state. The electrode regions are configured for direct and/or indirect application of thermal and/or electrical energy to heat or otherwise electrically modulate neural fibers that contribute to renal function or of vascular structures that feed or perfuse the neural fibers.

Neuromodulation catheters and associated systems and methods

Growing community of inventors

Roncadelle, Italy

Carlo Guala