Arizona State University

Other

Carl Wagner

Peter Jurutka

Pamela A Marshall

Bertram L Jacobs

Jeffrey O Langland

Arjan Van Der Vaart

Thomas Cahill

Guillermo Ruiz

The present disclosure relates to pharmaceutical compositions comprising caffeic acid chelates, kits, and methods for using such compounds and pharmaceutical compositions.

Pharmaceutical compositions comprising caffeic acid chelates

The invention provides compounds formula (I) and salts thereof: wherein R-Rhave any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, inflammation, hyperresponsiveness, allergic conditions, asthma, and psychotic disorders such as schizophrenia. The compounds are also useful to lower IL-4, IL-5, or IL-15 levels in an animal.

Substituted anilines for treatment of animal diseases

The invention provides compounds of formulae I, II, III, and IV: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers and Alzheimer's disease.

Therapeutic compounds

The invention provides a method for a disease or condition associated with dopamine deficiency (e.g. depression, schizophrenia, or Parkinson's disease) in a mammal in need of such treatment comprising administering a compound that binds to RXR to the mammal.

Therapeutic methods

The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.

Dihydroindene and tetrahydronaphthalene compounds

Isochroman compounds and methods of use thereof

The invention provides alkyl benzene compounds. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, inflammation, hyperresponsiveness, allergic conditions, asthma, and psychotic disorders such as schizophrenia. The compounds are also useful to lower IL-4, IL-5, or IL-15 levels in an animal.

The invention provides compounds formula (I) and salts thereof: wherein the bond represented by ---- is a single bond or a double bond, and R1 has any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, and psychotic disorders such as schizophrenia. 

The invention provides compounds and compositions that are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, and psychotic disorders such as schizophrenia.

The invention provides compounds of formulae (I), (II), (III), and (IV): and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers and Alzheimer's disease. 

The present invention relates to analogs of bexarotene and methods of use thereof.

Bexarotene analogs

Naphthyl-containing compounds having structural formula SR for use in organic light-emitting diodes (OLEDs). R may include an aromatic group, a heterocyclic group, or a group that is both aromatic and heterocylic. In some examples, R is phenyl, biphenyl, and thiophenyl. OLEDs including these compounds are shown to emit in a range between 400 nm and 700 nm. These OLEDs are suitable for devices including televisions, laptop computers, computer monitors, personal digital assistants, mobile phones, portable media players, watches, test devices, advertising displays, information displays, indication displays, and large-area light-emitting elements for general illumination. 

Naphthyl-containing compounds for light-emitting devices

A billfold of utmost simplicity and practicality, produced in only two operations, comprising a folded blank and having separate bill and credit card compartments. The bill compartment allows a portion of the bills to project beyond the body of the billfold so that a desired bill can be grasped and removed without opening up the billfold; a tab covers the projecting portion of the bills. Another tab which forms the end of the credit card pocket can be unfolded to allow access to the credit cards.

Growing community of inventors

Glendale, AZ, United States of America

Carl Wagner