National Jewish Health

National Jewish Medical and Research Center

Carl W White

Livia A Veress

Brian J Day

Kumuda C Das

The present invention is directed to methods of treatment of airway obstruction associated with fibrin-containing cast formation by administering a fibrinolytic agent.

Treatment for airway cast obstruction

Compounds may be administered to prevent or rescue organ injury following exposure to alkylating agents, such as sulfur mustards. The compounds may be substituted metalloporphyrins.

Methods for treating injury associated with exposure to an alkylating species

Disclosed are compositions and methods for decreasing the viscosity and/or cohesiveness of and/or increasing the liquefaction of excessively or abnormally viscous or cohesive mucus or sputum. The composition contains a protein or peptide containing a thioredoxin active-site in reduced state and optionally further contains a reducing system.

Product and process for liquefaction of mucus or sputum

A method to increase cellular MnSOD production in an animal to treat oxidative damage by administering a protein having a thioredoxin active-site in reduced state. A composition and a method to protect an animal from lung disease are provided.

Growing community of inventors

Denver, CO, United States of America

Carl W White