Burroughs Wellcome Co.

Carl W Sigel

Charles A Nichol

David Stanley Duch

Potent antiproliferative activity in combination with low inhibition of histamine N-methyltransferase has been found in a class of 2,4-diamino-6-(2,5-dialkoxybenzyl)-5-methylpyrido[2,3-d]pyrimidines.

Treatment with dialkoxy pyridopyrimidines

This application is directed to treatment of psoriasis with a pyrido pyrimidine compound such as 2,4-diamino-6-(3,4-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine.

Treatment with dialkoxy pyridopyrimidine compounds

Potent psoriasis activity in combination with low inhibition of histamine N-methyltransferase has been found in a class of 2,4-diamino-6-(2,5-dialkoxybenzyl)-5-methylpyrido[2,3-d]pyrimidines.

Growing community of inventors

Raleigh, NC, United States of America

Carl W Sigel