University of Utah Research Foundation

Carl Thomas Witter

Robert Andrew Palais

A method for clustering melting profiles of a plurality of nucleic acid samples, comprising measuring the fluorescence of each nucleic acid sample as a function of temperature to produce a respective raw melting curve for each respective nucleic acid sample, and clustering genotypes of the plurality of nucleic acid samples to form a plurality of clusters of melting curves. A system for analyzing a plurality of nucleic acid samples comprising an instrument for sequentially heating fluorescently detectable complexes while monitoring their fluorescence, a central processing unit (CPU) for performing computer executable instructions, and a memory storage device for storing computer executable instructions that when executed by the CPU cause the CPU to cluster genotypes of a plurality of nucleic acid samples.

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Salt Lake City, UT, United States of America

Carl Thomas Witter