Karykion Corporation

Children's Medical Center Corporation

Carl P Schaffner

Keith R Solomon

Michael R Freeman

William K Griesinger

Compositions and method of using the same for the removal of ticks embedded in the skin or tissue of a human or animal host and for preventing ticks from attaching themselves to and biting humans or other animals.

Method of removing ticks from the skin and reducing the risk of bites

Provided are compositions and an article for manufacture with an associated writing comprising the composition for the removal of ticks embedded in the skin or tissues of a human or animal host. Moreover a method is provided for removal of ticks embedded in the skin or tissues of a human or animal host by the topical application of the composition.

Method of removing ticks from the epidermal tissue of humans and other mammals

A method of prevention or treatment of a cholesterol-associated tumor is provided which comprises administering a therapeutically effective amount of an azetidinone-based cholesterol absorption inhibitor, preferably ezetimibe (SCH 58235) and/or its phenolic glucuronide, or at least one ezetimibe analog, e.g., SCH 48461 and SCH 58053, to a patient wherein the patient is either at risk of developing a cholesterol-associated tumor or already exhibits a cholesterol-associated tumor. Formulations of ezetimibe are also provided for the prevention or treatment of a cholesterol-associated tumor further comprising at least one other anticancer agent. An article of manufacture is also provided which comprises a container, instructions, and a composition, wherein the composition comprises a therapeutically effective amount of an azetidinone-based cholesterol absorption inhibitor, preferably ezetimibe or its phenolic glucuronide, and the instructions are for the administration of the composition for the prevention or treatment of a cholesterol-associated tumor.

Growing community of inventors

Hamilton, NJ, United States of America

Carl P Schaffner