US Government As Represented by the Secretary of the Army

Carl J Mason

Daniel L Klayman

John P Scovill

T Scott Griffin

Joseph F Bartosevich

This invention relates to various 2-acetyl- and 2-propionylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malaria or bacterial infection. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.

2-acetyl-and 2-propionylpyridine thiosemicarbazones

Medicinal 2-acetyl- and 2-propionylpyridine thiosemicarbazones and

Method for treating bacterial infections with 2-acetyl- and

This invention relates to various 2-acetyl- and 2-propionylpyridine thioscarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malaria or bacterial infection. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.

Method for treating gonorrhea infections with 2-acetyl- and

2-Acetyl-and 2-propionylpyridine thiosemicarbazones as antimalarials

2-Acetyl-and 2-propionylpyridine thiosemicarbazones

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Silver Spring, MD, United States of America

Carl J Mason