University of Georgia Research Foundation Inc

Chembio Diagnostic Systems, Inc.

Candace McCombs

Frederick Quinn

Russell K Karls

Javanbakhsh Esfandiari

Konstantin Lyashchenko

The present invention includes cold-adapted, acid-fast bacterium for use as a vaccine and a vaccine vector. In preferred embodiments, the cold-adapted, acid-fast bacterium is a, for example,

Microbial vaccine and vaccine vector

Systems, methods, and compositions for a diagnostic method for detecting TB in non-human primates that is easy to use, sensitive, and specific. The method utilizes recombinant mycobacterial antigens, such as polyfusion proteins. The method utilizes an antigen-antibody-antigen arrangement to detect TB infection in nonhuman primates. The method can detect IgM antibodies to TB, in addition to IgG antibodies, providing ability to detect TB earlier in nonhuman primate TB infection as compared to conventional TB tests.

Growing community of inventors

Athens, GA, United States of America

Candace McCombs