Novartis Ag

Ninebot (Changzhou) Tech Co., Ltd

Huawei Technologies Co., Limited

Jiangsu Xcmg Construction Machinery Research Institute Ltd.

Can Wang

Xianglin Zhao

Pascal Furet

Robin Alec Fairhurst

Robert Mah

Bo Han

Catherine Leblanc

Lv Liao

Jing Xiong

Nicole Buschmann

Thomas Knöpfel

Pierre Nimsgern

Sebastien Ripoche

Feng Gao

Jianguang Zhou

Dale Porter

Diana Graus Porta

Benjamin Martin

Zhongcheng Min

Weiyong Kong

Yu Gai

Chutian Shu

Yi Zhao

Huocheng Wei

Ruidong Wang

Xuanyu Huang

Jibin Zhao

Ronghui Lv

Peng Fu

Yadong Lu

Shaofeng Rong

Matthew J LaMarche

Liping Zhang

Jorge Garcia Fortanet

Ramulu Poddutoori

Markus Wartmann

Xiaolong Li

Thomas Knoepfel

Youzhen Wang

Ke Chen

Andreas Weiss

Carolina Haefliger

Masato Murakami

Michael Palmer

Nafeeza Hafeez

Franck Mallet

Julie Martz

Yuefan Gao

Min Xia

Chao Ren

Yao Ma

Ang Ji

Thomas KNÖPFEL

The present disclosure discloses a folding device and a scooter having the folding device. The folding device includes: a first folding seat and a second folding seat arranged opposite to each other and rotatably coupled to each other, the first folding seat being located above the second folding seat; a first locking assembly rotatably coupled to the second folding seat, the first locking assembly being rotatable between a first position and a second position; a second locking assembly configured to clamp or release the first folding seat and the first locking assembly; and a reset member coupled to at least one of the first locking assembly and the second locking assembly.

Folding device and scooter

A meshing structure for plate welding, and a tack-free welding device and method are provided. The device comprises a connecting frame, a welding gun, and a cutting mechanism, the welding gun is fixed on the connecting frame, and the cutting mechanism is connected to the connecting frame. The meshing structures are disposed on welded plates, and after being assembled, the two plates can be restrained by the meshing structures in multiple dimensions. Before welding, edges of the plates are cut according to the form of the meshing structures, then the plates are assembled and meshed; after the position of the welding gun is adjusted, the cutting mechanism and the welding gun are driven by a welding robot or a special welding machine to move along a weld; and the meshing structures are removed by the cutting mechanism, and then normal welding is performed by the welding gun.

Meshing structure for plate welding and tack-free welding device and method

A scooter including a frame and a casing. The casing covers an outer peripheral side of the frame and is made of plastics.

Scooter

The present disclosure provides a foot-deck device and a vehicle. The foot-deck device includes: a bracket; two deck assemblies oppositely disposed on the bracket, the two deck assemblies each including a deck and a rotating shaft, the rotating shafts being pivotally disposed on the bracket, and the decks being disposed on the rotating shafts; and a linkage mechanism, the rotating shaft of one deck assembly being coupled to the rotating shaft of the other deck assembly through the linkage mechanism, the linkage mechanism being used to cause the rotating shafts of the two deck assemblies to rotate synchronously and cause the decks of the two deck assemblies to rotate synchronously to respective folded positions or unfolded positions.

Foot-deck device and vehicle

A damping mechanism and a vehicle are provided. The damping mechanism includes: a spindle; an elastic cushion assembly used to couple the spindle and the vehicle body; a coupling arm having a first end used to be fixedly coupled to an axle of the wheel and a second end pivotally coupled to the spindle; and a locking assembly provided between the coupling arm and the spindle and used to switch the coupling arm and the spindle between at least two locking states and a unlocking state. In the unlocking state, the coupling arm is rotatable, and in the locking states, the coupling arm is locked; in each of the locking states, the coupling arm is in different locking positions relative to the spindle; and when the coupling arm is in different locking positions, the coupling arm is at different angles to a horizontal plane.

Damping mechanism and vehicle

A shock absorber and a transportation tool. The shock absorber includes a first rotating arm; a second rotating arm pivotally coupled to the first rotating arm; and a torsion bar spring having a first end coupled to the first rotating arm and a second end coupled to the second rotating arm, wherein an included angle between the first rotating arm and the rotating arm has a set value. The shock absorber has a simple structure and good shock absorption effect and adjustable stroke.

Shock absorber and transportation tool

The present invention relates to a method of synthesizing a compound of formula (I) also referred to as 4-(((2S,4S)-(4-ethoxy-1-(((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl))benzoic acid, or a pharmaceutically acceptable salt thereof, and/or intermediates thereof, their use as pharmaceuticals and pharmaceutical compositions and the use of intermediates for preparing a compound of formula (I), or a pharmaceutically acceptable salt thereof.

Chemical process for preparing phenylpiperidinyl indole derivatives

A stem assembly and an electric vehicle are provided. The stem assembly includes: a stem telescoping mechanism including a first hollow tube, a second hollow tube, and a locking mechanism, the locking mechanism having a locked state and an movable state; a handle folding mechanism arranged to the stem telescoping mechanism, the handle folding mechanism including a handle assembly and a first limiting member, the first limiting member being movably arranged, and having a first limiting position and a first evading position; and a driving mechanism connected to both the locking mechanism and the first limiting member, and configured to be operated to control the stem telescoping mechanism and the handle folding mechanism to synchronously move.

Stem assembly and electric vehicle

The present invention relates to a method of synthesizing a compound of formula (I) also referred to as 4-((2S,4S)-(4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl))benzoic acid, or a pharmaceutically acceptable salt thereof, and/or intermediates thereof, their use as pharmaceuticals and pharmaceutical compositions and the use of intermediates for preparing a compound of formula (I), or a pharmaceutically acceptable salt thereof.

Embodiments of the present invention disclose a propagation path search method. In one embodiment, the method includes: defining a target three-dimensional object, where the target three-dimensional object is configured to describe full space; setting a signal transmission point in internal space of the target three-dimensional object to perform initial beam modeling of a signal point source, where the signal transmission point is used to transmit an initial beam; tracking the initial beam to determine a propagation manner generated by the initial beam in the three-dimensional object; and determining that a path corresponding to a target beam is an effective path when the target beam reaches a signal receiving point, where the target beam is included in the initial beam, or is obtained after the initial beam is split or changed.

Propagation path search method and apparatus

The present invention relates to therapeutic uses of compounds of formula (I) or a pharmaceutically acceptable salt thereof 

Use of ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors

A pharmaceutical combination comprising N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, or a pharmaceutically acceptable salt thereof, and at least one active ingredient, as defined herein, or a pharmaceutically acceptable salt thereof, and optionally a pharmaceutically acceptable carrier, for simultaneous or sequential administration; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.

Pharmaceutical combinations

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.

Ring-fused bicyclic pyridyl derivatives as FGFR4 inhibitors

The present invention relates to particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide, to a process of making said particles, to pharmaceutical compositions comprising said particles and to method of treating cancers using said pharmaceutical compositions.

Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide

Growing community of inventors

Suzhou, China

Can Wang