Phytrix Ag

C Warren Olanow

Hildebert Wagner

Rob Van Der Giessen

Andrew Lees

The present invention provides pharmaceutical compositions comprisingseeds or one or moreseed components, substances, fractions or mixtures or substances obtained therefrom. Furthermore, the invention relates to the use ofseed powder or one or morecomponents, substances, fractions or mixtures or substances obtained therefrom for the preparation of a pharmaceutical composition for preventing, alleviating or treating neurological diseases. Additionally, the invention relates to the use ofseeds for the preparation of a pharmaceutical composition for neuroprotection or neurostimulation and to methods of preparing extracts ofwhich can be used for the preparation of a pharmaceutical composition for treating neurological diseases. Finally, the invention relates to the use ofseeds for the preparation of a pharmaceutical composition for the treatment of Parkinson's Disease to obtain a broader therapeutic window in L-Dopa therapy, to delay a need for combination therapy, to obtain an earlier onset and longer duration of L-Dopa efficacy, and to prevent or alleviate acute and chronic L-Dopa toxicity.

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Rye, NY, United States of America

C Warren Olanow