Mcneil Ab

C Royce Rasmussen

Allen B Reitz

Frank John Villani, Jr

Malcolm K Scott

Henry I Jacoby

Compounds of the general formula I ##STR1## wherein A is N; Ar is aryl, substituted aryl or benzofuranyl, wherein the substituents are selected from C.sub.1 -C.sub.8 alkoxy; B is CO or CH.sub.2 and HET is selected from any of piperizine, piperidine, hexahydroazepine, morpholine, thiomorpholine or pyrrolidine, which may be substituted with one of more oxo groups are disclosed as novel antipsychotic agents. Pharmaceutical compositions and methods of treating convulsions employing such compounds of formula I are also disclosed.

Thiophene and pyridine antipsychotic agents

N-aryl-N'-imidazol-2-ylureas useful for their antihypertensive, antidiarrheal, anti-irritable bowel syndrome, and anti-secretory activities.

Growing community of inventors

Lansdale, PA, United States of America

C Royce Rasmussen