Other

Vyteris, Inc.

C Randolph Bock

Burton H Sage

John L Haynes

Vilambi Reddy

John R DeNuzzio

The present invention claims an apparatus for transdermal delivery of medicaments, with novel electrode systems, which avoids burns caused by changes in pH or excessive current applied at the sight of delivery, which is low in cost and easy to manufacture. In the present invention, preferably, the anode of the electrode system is predominantly formed from a low-cost bulk base metal which includes a coating of a precious metal thereon. The cathode of the electrode system is preferably formed from an chemically inert material which is a poor electron condutor and is coated on a good electron conductive material which has poor chemical stability. The electrode system of the present invention is highly efficient, easy to manufacture and cost-effective.

Low cost electrodes for an iontophoretic device

A device for electrically assisted transport of molecules into the skin has a renewable power source and a means for electrically assisted transport of molecules in solution through the skin of an animal. The device has an anode and a battery electrolyte in fluid communication in a disposable part of the means for electrically assisted transport of molecules in solution. The device has an air cathode on a reusable part of the means for electrically assisted transport so that when the reusable and disposable parts join, the battery electrolyte and the air cathode are in fluid communication. The power source is thereby renewed and electrically connected to the means for electrically assisted transport. A method for renewing and replenishing a power source for the device for electrically assisted transport of molecules in solution provides means for electrically assisted transport having a reusable part and a disposable part. The method includes providing the reusable part with an air cathode and an anode contact on a support and providing the disposable part having an anode in fluid communication with a battery electrolyte on a carrier. The method renews the power source by joining the support and the carrier. The battery electrolyte, the air cathode and the anode are thus joined in fluid communication and the anode with the anode contact are electrically connected.

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Durham, NC, United States of America

C Randolph Bock