Hitachi Chemical Diagnostics, Inc.

C Benjamin Wooley

William J Sell

Adonis Kassinos

Brett Wilmarth

Karen Ding

Renee Ryan

Emi Zychlinsky

Michael Zatzke

Donald Marino

Dianna Innerst

Sandy Yamada

An enclosed chamber is used in a system for screening of a liquid specimen through binding assays. The enclosed chamber includes an inlet, an outlet, and a plurality of discrete reactant containing wells communicated by a common reagent flow path between the inlet and the outlet. A transparent member or coverslip defines on an inside thereof the plurality of wells. Each well has a bottom for receiving an allergent/antigen/reactant, which emits light upon reacting. The coverslip can optionally define at least one lens at each well. A bottom encloses the plurality of wells and defines between the inlet and the outlet a common reagent flow path between the inlet and the outlet. This bottom defines for each of the plurality of wells a flow-diverting member. An opaque partition is disclosed for surrounding the individual lenses and generally isolating the light path from each well.

Optically and fluidically enhanced in vitro diagnostic test chamber

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Chapel Hill, NC, United States of America

C Benjamin Wooley