Daewoong Pharmaceutical Co., Ltd.

Daewoong Bio Inc.

Byung Goo Lee

Young Soo Kim

Soo Jin Choi

Hee Kyoon Yoon

Hye Jin Kim

Yong Suk Jin

Yong Kim

In Woo Kim

Ji Duck Kim

Sung Woo Park

Sung Jae Lee

Seong Cheol Moon

Sun Ah Jun

Joon Hwan Lee

Kwang Joo Kim

Seong Soo Oh

Young Mook Lim

Yeon Jung Yoon

Yoon Seok Song

Wol Young Kim

Young Soo R&D Strategy Team Kim

Soo Jin R&D Strategy Team Choi

Sung Jae R&D Strategy Team Lee

The present invention relates to an improved method for synthesizing meropenem trihydrate[(1R,5S,6S)-2-[((2'S,4&#x2032;S)-2&#x2032;-dimethylaminocarbozyl)pyrrolidin-4&#x2032;-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid, trihydrate], which is a novel carbapenem antibiotic.

Method for preparing meropenem using zinc powder

The present invention relates to novel Forms A, B, C, D, E, F and G of crystalline 9-[2-[phosphonomethoxy]ethyl]adenine bis-pivaloyloxymethyl ester, i.e., adefovir dipivoxil, and processes for preparing them. According to the present invention, said novel crystal forms having a high purity can be obtained by a simple method and in a high yield.

Crystal forms of adefovir dipivoxil and processes for preparing the same

This invention relates to a method of preparing a benzoimidazole derivative at high purity and high yield so as to enable the production of the benzoimidazole derivative compound as an antagonist against a vanilloid reactor-1, and particularly to a method of preparing a benzoimidazole derivative at high purity and high yield, wherein the benzoimidazole derivative is synthesized using a novel intermediate, namely, benzaldehyde, and thereby the preparation process is simple so that it can be applied to production.

Method of preparing benzoimidazole derivatives

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Suwon, South Korea

Byung Goo Lee