Seoul National University

Snu Rdb Foundation

Amorepacific Corporation

Neopharm Co., Ltd.

Genechem Inc.

Science@home Inc.

Byung Gee Kim

Sang Hyuk Lee

Sung Jun Park

Han Bit Kim

Duck Hee Kim

Jun Seong Park

Eun Mi Kim

Se Kyoo Jeong

Min-Ho Cha

Kwon Young Choi

Jeong Eun Jeon

Yoon Sik Lee

Eun Young Hong

Uk Jae Lee

Jin Suk Woo

Sun Youp Kang

Ji Young Yang

Yun Hee Choi

Won Min Seo

Bu Mahn Park

Young Soo Jung

In Kang Hur

Sang Hee Shim

Tae Geon Gil

June Hyung Kim

Dea Hee Kim

Kyoung Soon Jang

Bong Woo Kim

Hyun Kim

Prasad Pandey Bishnu

Su Hyun Seo

The present invention relates to a cross-linked material having adhesion prepared by using tyrosinase derived from, preparation method thereof and application thereof, and specifically relates to the hydrogel composition having adhesiveness. The hydrogel composition having adhesiveness of the present invention is injectable through an injection or spraying, and can be used in 3D printing or preparation of adhesive hydrogel medical film, etc.

Cross-linking material having adhesive strength, prepared using-derived tyrosinase, preparation method therefor, and application thereof

The present invention relates to a biopolymer-based hydrogel as a functional biomaterial produced by crosslinking in the presence of a photopolymerization initiator. The hydrogel of the present invention is elastic so as to be adapted to various shapes in both in vivo and in vitro applications. It is biocompatible, achieving maximum effects on wound healing as wound dressing and tissue adhesion preventing material. The present invention also relates to a method for producing the biocompatible hydrogel.

Tyrosine peptide cross-linked biocompatible hydrogel and method of production

The present invention relates to a method for producing a lysine carboxylase mutant strain, characteristics of the mutant strain, a gene encoding the lysine decarboxylase mutant strain, and a method for producing cadaverine using the same. The present invention provides lysine decarboxylase derived fromimproved through a protein engineering variation. In addition, the lysine decarboxylase mutant strain of the present invention increases activity, pH stability, and thermal stability at the time of producing cadaverine, thereby reducing production costs, through increasing a yield and productivity.

Method for developing lysine decarboxylase mutant and application thereof

The present invention provides an &#x3b1;-1,3 fucosyltransferase mutant having an increased expression level of soluble protein and increased activity, a DNA encoding the &#x3b1;-1,3 fucosyltransferase mutant, a recombinant vector comprising the DNA encoding the &#x3b1;-1,3 fucosyltransferase mutant, a host cell transformed with the recombinant DNA vector, an extract of the host cell, a method for producing 3-fucosyloligosaccharide, a method for preparing an &#x3b1;-1,3 fucosyltransferase mutant, and a method for screening an &#x3b1;-1,3 fucosyltransferase mutant. The &#x3b1;-1,3 fucosyltransferase mutant of the present invention has a significantly increased soluble protein expression level and activity.

Helicobacter pylori &#x3b1;-1,3 fucosyltransferase gene and protein with improved soluble protein expression and activity, and thereof application for synthesis of &#x3b1;-1,3 fucosyloligosaccharide

The present invention relates to a pharmaceutical composition and a cosmetic composition, which contain, as an active ingredient, a novel pseudo compound having similar structural characteristics to natural ceramide 1, or a pharmaceutically acceptable salt or solvate thereof, and the composition containing the compound of the present invention as an active ingredient has an excellent effect of enhancing a skin barrier function, thereby exhibiting an effect of alleviating inflammatory skin diseases, and has an excellent skin barrier improving function and an excellent skin moisturization enhancing effect.

Pseudo ceramide compound, and pharmaceutical composition and cosmetic composition comprising same

The present invention relates to the novelsp. GIN611 KCTC11708BP or to cell extracts thereof, to a novel oxidoreductase which exhibits a glycolytic activity, to a gene encoding the oxidoreductase, to a recombinant strain comprising recombinant vector proteins or to an expression vector encoding recombinant proteins, and to a method for the glycolysis of natural products using same as a biocatalyst. The present invention also relates to a method for producing aglycones from a variety of natural products using same. The novel oxidoreductase separated from the novel microorganism of the present invention does not belong to a glucosidase group but belongs to an oxidoreductase group, and has a glycolytic activity for natural products. The novel oxidoreductase oxidizes the sugar in the aglycones of natural products, thereby producing a variety of aglycones.

Soil microorganism, novel oxidoreductase separated from the soil microorganism, gene encoding the oxidoreductase, and method for producing aglycones using the microorganism, the oxidoreductase and the gene

The present invention relates to a novel N-acetylglucosamine-2-epimerase and a method for preparing CMP-N-acetylneuraminic acid, more specifically, relates to a N-acetylglucosamine-2-epimerase derived fromNCTC 9343, and a method for preparing CMP-N-acetylneuraminic acid using said N-acetylglucosamine-2-epimerase. According to the present invention, CMP-N-acetylneuraminic acid can be produced economically in a large amount through a one-step reaction using cytidine monophosphate and N-acetyl-D-glucosamine which are inexpensive substrates.

N-acetylglucosamine-2-epimerase and method for producing CMP-neuraminic acid using the same

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Seoul, South Korea

Byung Gee Kim