East Carolina University

Bryent Tucker

Cheng Chen

T Bruce Ferguson, Jr

Thomas Bruce Ferguson, Jr

Kenneth Michael Jacobs

Sunghan Kim

William Hempstead

Xin Hua Hu

Taylor Forbes

Jiahong Jin

Systems for obtaining an image of a target are provided including at least one multi-wavelength illumination module configured to illuminate a target using two or more different wavelengths, each penetrating the target at different depths; a multi-wavelength camera configured to detect the two or more different wavelengths illuminating the target on corresponding different channels and acquire corresponding images of the target based on the detected two or more different wavelengths illuminating the target; a control module configured synchronize illumination of the target by the at least one multi-wavelength illumination module and detection of the two or more different wavelengths by the camera; an analysis module configured to receive the acquired images of the target and analyze the acquired images to provide analysis results; and an image visualization module modify the acquired images based on the analysis results to provide a final improved image in real-time.

Near-infrared fluorescence imaging for blood flow and perfusion visualization and related systems and computer program products

Some embodiments of the present inventive concept provide a multispectral imaging system including a first light source, the first light source having a first wavelength configured to produce a non-coherent illumination to image a sample; a second coherent light source, different from the first light source, having a second wavelength, different from the first wavelength, configured to image the sample simultaneously with the first light source; a camera configured to simultaneously receive information related to the first and second light sources from the sample, wherein light at the first wavelength is configured to image a surface of the sample into the camera and light at the second wavelength is configured to penetrate the sample and provide information related to the penetrated sample to the camera; and a processor configured to combine the received information related to the first and second light sources and generate a synthesized image of the anatomical structure and the physiology of blood flow and perfusion of the sample in terms of blood flow rate distribution.

Determining peripheral oxygen saturation (SpO2) and hemoglobin concentration using multi-spectral laser imaging (MSLI) methods and systems

Multispectral imaging systems are provided including an illumination control module configured to image a sample and provide an imaging output sequence including images and data; a multi-spectral physiologic visualization (MSPV) module, a peripheral oxygen saturation (SpO) module and a physiologic status parameters (PSP) module configured to receive the imaging output sequence of the illumination control module simultaneously. The MSPV module is configured to provide real-time blood flow distribution visualization of a field of view (FOV) responsive to the received imaging output sequence. The SpOmodule is configured to provide real-time SpOinformation at a tissue surface level for the FOV responsive to the received imaging and output sequence. The PSP module is configured to derive status parameters in real-time from metadata associated with the received imaging and output sequence of the FOV. The system further includes a processing engine configured to integrate and analyze the real-time blood flow distribution visualization, SpOinformation and derived status parameters.

Systems for detecting vascular and arterial disease in asymptomatic patients and related methods

Growing community of inventors

Rocky Mount, NC, United States of America

Bryent Tucker