Arrinex, Inc.

Leland Stanford Junior University

Other

Bryant Lin

Vahid Saadat

Mojgan Saadat

Paul J Wang

David Moosavi

William Jason Fox

Ross Daniel Venook

Brian Fahey

Friedrich B Prinz

Robert Chris Allison

Kenneth L Carr

Tatum Tarin

Amin Al-Ahmad

Richard Goode

Baharan Kamousi

Dorothea Koh

Marie Guion-Johnson

Paul Zei

Matthew Siljander

Peter Hwang

Devices and methods for treating rhinitis are described where the devices are configured to ablate a single nerve branch or multiple nerve branches of the posterior nasal nerves located within the nasal cavity. A surgical probe may be inserted into the sub-mucosal space of a lateral nasal wall and advanced towards a posterior nasal nerve associated with a middle nasal turbinate or an inferior nasal turbinate into a position proximate to the posterior nasal nerve where neuroablation of the posterior nasal nerve may be performed with the surgical probe. The probe device may utilize a visible light beacon that provides trans-illumination of the sub-mucosal tissue or an expandable structure disposed in the vicinity of the distal end of the probe shaft to enable the surgeon to visualize the sub-mucosal position of the distal end of the surgical probe from inside the nasal cavity using, e.g., an endoscope.

Apparatus and method for treating rhinitis

The present disclosure provides apparatuses and methods for treating conditions such as chronic daily headache, cluster headache, tension headache, migraine, or acute headache of a patient. In example methods, a cryotherapy element is introduced into the nasal cavity or pterygopalatine fossa to cool or cryoablate at least one of a nasal nerve tissue or nasal blood vessel. The cryotherapy element may be introduced into the nasal cavity in a collapsed position, and prior to cooling a target treatment site may be expanded to an expanded configuration.

Systems and methods for improved treatment of headache

Apparatus and methods for treating and monitoring conditions such as rhinitis are disclosed herein. The technology utilizes ultrasound scans to identify target treatment sites, and monitor the treatment of a patient undergoing a treatment. The treatment may be an ablation treatment of a nasal nerve, for example the PNN for the treatment of nasal conditions, such as rhinitis. The ultrasound scans are performed within the nasal cavity with an ultrasound probe or a combined ultrasound and ablation probe and may use Doppler, A-mode, B-mode, M-mode or other ultrasound and non-ultrasound modalities to detect and monitor the target treatment sites.

Systems and methods for locating blood vessels in the treatment of rhinitis

An ablation therapy system is disclosed comprising an ablation catheter system for treating atrial fibrillation (AF). The ablation catheter system comprises a catheter body including a lumen for receiving a visualization catheter, an ablation element for ablating tissue in a patient's heart having abnormal electrical activity, a support assembly for supporting the ablation element, the support assembly being supported by the catheter assembly. The support assembly includes a lumen to receive the visualization catheter, wherein the support assembly is configured to rotate and/or pivot with respect to the catheter body.

Ablation catheter system and method for deploying same

A method is provided that includes providing a monitoring apparatus including one or more modules within a target cavity or lumen of a body. The one or more modules are provided within the target cavity or lumen in a first state in which the monitoring apparatus is configured to remain within the target cavity or lumen. The method further includes monitoring physiological conditions of the body using one or more sensors within the one or more modules, and providing the one or more modules in a second state in which the monitoring apparatus is configured to exit the target cavity or lumen.

Method and apparatus for in-vivo physiological monitoring

The disclosure relates to methods and devices for monitoring e.g., fatigue levels by measuring a subject's body core temperature. In one embodiment, microwave radiometry is used to measure such core temperature.

Devices and methods for exercise monitoring

A method of modifying properties of intrinsic tissue of an organ is provided. The method includes providing an organ, where a first electrode is disposed proximal to the organ first end. The first electrode has a surface area and insulator. A second electrode is disposed opposite the first electrode, where the organ is disposed between the first electrode and the second electrode. The second electrode has surface area and surface insulator. An organ-shaping device is provided that is disposed on the organ between the electrodes, where the organ-shaping device deforms the organ middle section along at least one lateral direction between the electrodes. An electric current is provided between the first second electrodes, where a current density gradient is provided by the electrode surface areas and the deformed organ middle section, and the properties of the intrinsic muscle tissue are modified according to the current density gradient.

Device and method to treat tissue with electric current

Techniques for discrimination of heart rhythms in cardiac rhythm management devices include determining a current covariance matrix of multiple electrograms measuring each current heart beat, determining a distance measure between the current covariance matrix and a predetermined covariance matrix of the multiple electrograms measuring at least one different heart beat; and determining whether the heart beat represents ventricular tachycardia based on the distance measure.

Method to discriminate arrhythmias in cardiac rhythm management devices

The system of the preferred embodiments includes a first rotational element, a second rotational element, and a therapeutic source coupled to the rotational elements. The system permits simultaneous attachment to and movement around a surface of tissue, preferably during an ablation procedure (either during lesion creation or between lesion creation events), or during any other suitable procedure. The therapeutic source functions to translate along the path of tissue and deliver therapy as the first and second rotational elements rotate and roll along the path of tissue. The therapeutic source preferably delivers contiguous doses of therapy along the path of tissue. The system is preferably designed for delivering therapy to tissue and, more specifically, for delivering therapy to cardiac tissue. The system, however, may be alternatively used in any suitable environment and for any suitable reason.

Growing community of inventors

Menlo Park, CA, United States of America

Bryant Lin