Metabolon, Inc.

Bryan Wittmann

John A Ryals

Michael V Milburn

Matthew W Mitchell

Lining Guo

Adam D Kennedy

Jacob Wulff

Andrea Eckhart

Thomas J Jönsson

Ryan Douglas Michalek

Methods are described herein for small molecule biochemical profiling of an individual subject for diagnosis of a disease or disorder, facilitating diagnosis of a disease or disorder, and/or identifying an increased risk of developing a disease or disorder in the individual subject. Aberrant levels of small molecules present in a sample from an individual subject are identified and diagnostic information relevant to the individual subject is obtained based on the identified aberrant levels. The obtained diagnostic information includes one or more of an identification of at least one biochemical pathway associated with the identified subset of the small molecules having aberrant levels, an identification at least one disease or disorder associated with the identified subset of the small molecules having aberrant levels, and an identification of at least one recommended follow up test associated with the identified subset of the small molecules having aberrant levels.

Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment

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Rougemont, NC, United States of America

Bryan Wittmann