University of Wyoming

Bryan Hubert Ray

Keith T Carron

Roberta A Sulk

A Raman spectroscopy technique allows an analyte, a paramagnetic particle, and a spectral enhancement particle to combine in solution and for the combination product to be localized by a magnetic field for analysis. The spectral enhancement particle may be comprised of an active SERS metal particle with or without a material coating. The spectral enhancement particle may function as a reporter for the presence of the analyte or merely increase the magnitude of the Raman spectrum of the analyte. The technique is applicable to both immunoassays and chemical assays. Multiple spectral enhancement particle reporters may be measured in a single assay that can detect multiple analytes using the SERS effect.

System and method for Raman spectroscopy assay using paramagnetic particles

An assay and method of making same for use in SERS spectroscopy. The assay includes colloidal particles of a metal, which have been lyophilized. The lyophilized particles of metal produce a SERS active solution when reconstituted. The lyophilized particles of metal may be provided in a container in an assay system.

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Laramie, WY, United States of America

Bryan Hubert Ray