University of Iowa Research Foundation

Bryan G Allen

Yusung Kim

Ryan T Flynn

Michael K Schultz

Douglas R Spitz, Jr

Xiaodong Wu

Stephen Baek

Hongtao Ding

Fenghuang Zhan

Junyi Xia

Timothy J Waldron

Brian J Smith

Brennen N Wears

Garry R Buettner

Yusen He

Joseph Cullen

Joshua Schoenfeld

John Buatti

Methods and systems for image segmentation and analysis are described. A predictive model may be trained to identify and/or extract a rich set of image features with extensive prognostic value. For example, the predictive model may be trained to identify and/or extract features that that may be visualized to identify areas of interest (e.g., high-risk regions, etc.) within or adjacent to an object of interest, such a tumor. The predictive model may be trained to identify and/or extract features that that may predict a health related outcome, such as cancer patient survival/death, and modify therapeutic outcomes, such as diagnosis and treatment.

Methods and systems for image segmentation and analysis

Systems and methods for low energy radiation x-ray radiation therapy system for use at a target within a cavity of a subject. In an aspect, the system uses an aperture shaping device used to shape the radiation beam from the low energy radiation source. In an aspect, the aperture shaping device includes a plurality of leaf assemblies which include leaves configured to form the aperture and engage the radiation beam. In an aspect, the present invention utilizes a geared mechanics approach to create an aperture using only one dial input. The design ensures that the field size of the collimator remains a constant shape as it is opened and closed. In an aspect, the overall size of the collimator may be scaled to accommodate various radiation therapy requirements.

System and method for an intensity modulated radiation therapy device

The invention provides compositions and methods to treat a hyperproliferative disorder with ascorbate or a pharmaceutically acceptable salt thereof, at least one chelating agent that enhances ascorbate redox cycling (EDTA) to form HO, and one or more anti-cancer therapies.

Compositions and methods for cancer therapy

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Iowa City, IA, United States of America

Bryan G Allen