Roche Diagnostics Gmbh

Transoma Medical, Inc.

Aalborg Universitet

Obi Aps

Bruno Graversen

Claus Jepsen

Kevin Charles Johnson

Gregory M Smith

John L Arnold

Luke Strawn

Kathy Lynn Sherwood

Jesper Tange

Stephen Edward Rees

Lisha Shastri

Lars Pilegaard Thomsen

Bjarne Flou

The present invention relates to a method for identification of tissue hypoxia from measurements of acid-base and oxygenation status from venous and/or arterial blood.

Identification and quantification of the degree of tissue hypoxia

The present invention relates to method for providing values of measured and/or estimated arterial oxygenation (SO2, SO2, SpO2) based on measuring values of blood acid/base status in a venous blood sample (VBGM, VBG). A conversion of the venous blood values is made by applying a mathematical model for deriving blood acid/base status and oxygenation status into estimated or predicted arterial blood values (ABG). Furthermore, if a value of measured and/or estimated arterial oxygenation value is below a corresponding venous oxygenation value, then estimating the arterial oxygenation value is made with a replacement value being a function of the corresponding venous oxygenation value. The advantage is that converting venous blood value to arterial blood values will be possible by providing arterialized blood gas and acid-base values for a higher percentage of clinical samples previously not possible.

Method for estimating arterial blood values

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Hadsund, Denmark

Bruno Graversen