Sanofi-Synthelabo

Sanofi

Sanofi-Aventis

Bruno Franc

Olivier Monnier

Christian Hoff

Chenkou Wei

San Kiang

Mark D Lindrud

Antoine Caron

The invention relates to a novel crystalline form of irbesartan to pharmaceutical compositions containing it, to processes for preparing it, and to a method for treating cardiovascular diseases utilizing it.

Form of irbesartan, processes for obtaining the said and pharmaceutical compositions containing it

The invention relates to a novel crystalline form of irbesartan, to pharmaceutical compositions containing it, to processes for preparing it, and to a method for treating cardiovascular diseases utilizing it.

Form of irbesartan, methods for obtaining said form and pharmaceutical compositions containing same

The invention relates to a method of crystallizing a tetrahydropyridine derivative, to the novel crystalline forms thereby obtained and to the pharmaceutical compositions containing said tetrahydropyridine derivative in a given crystalline form as the active principle.

Method for the crystallization of a tetrahydropyridin derivative and resulting crystalline forms

The invention relates to a process for obtaining procyanidol oligomers according to which: an appropriate plant is treated by means of an extractive mixture composed of water, of a water-miscible organic solvent capable of dissolving the procyanidol oligomers and of sodium chloride, the crude mixture of procyanidol oligomers obtained is purified by removal of the extractive mixture and extraction of the residue, the extractive mixture optionally being recycled in the stage of treatment of the plant, the procyanidol oligomers are recovered in a pure form by precipitation.

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Saze, France

Bruno Franc