Schering Corporation

Other

Bruce L Murphy

Doris P Schumacher

Jon E Clark

A novel process for regioselectively preparing oxazoline compounds is disclosed. The process utilizes an amino alcohol, a cyano compound, a base and a dihydric alcohol solvent, a polyhydric alcohol solvent or mixtures thereof.

Process for preparing oxazoline compounds

There is disclosed a high yielding process for converting a hydroxy alkyl oxazolidine compound to the corresponding fluoro derivative by reacting the hydroxy compound with .alpha., .alpha.-difluoroalkylamine under pressure.

Pressurized fluorination of hydroxy alkyl groups

Compounds of the formula: ##STR1## are produced, with the variables as indicated within.

3-phenethyl-2-benzene-amides or aza-derivatives thereof

Certain benzocycloheptapyridine compounds with fluorine substitution across the exocyclic double bond are prepared and they are useful as antihistaminic agents.

Antihistaminic fluoro substituted benzocycloheptapyridines

A process for the preparation of piperidylidene-dihydro-dibenzo[a,d]cycloheptene or aza-derivatives thereof and intermediates in such process are disclosed.

Process for preparing piperidylidene dihydro-dibenzo(a,d)-cycloheptenes

Apparatus for trimming Christmas trees or the like to a uniform configuration. The apparatus includes a self-leveling cutter support frame, and a number of knive-like cutting blades mounted on the frame for rotation at high speed. The cutting frame is selectably extendable to accommodate trees having a range of lengths.

Growing community of inventors

Glen Ridge, NJ, United States of America

Bruce L Murphy