Knoll Aktiengesellschaft

The Boots Company Plc

Bruce Jeremy Sargent

David N Johnston

James Edward Jeffery

David John Heal

Maria Isabel Fernandez Fernandez

John R Housley

Andrew Philip Crew

Antonin Kozlik

Kenneth J Nichol

Alan Martin Birch

Frank Kerrigan

Patricia Lesley Needham

Keith Frank Martin

Patricia L Needham

Maria Aranzazu Villanueva Inurrategui

Heterocyclcarboxamide derivatives and their use as therapeutic agents

1,2,4-triazolo�4,3-b!pyridazine derivatives and their use

Pharmaceutical compositions

Isoquinoline derivatives as therapeutic agents

Tetrahydroisoquinoline compounds of formula I ##STR1## and pharmaceutically acceptable salts thereof, in which: R.sub.1 represents one or more substituents selected from H, halo, hydroxy, alkyl (optionally substituted by hydroxy), alkoxy, alkylthio, alkylsulphinyl, alkyl-sulphonyl, nitro, cyano, polyhaloalkyl, polyhaloalkoxy, phenyl (optionally substituted by one or more of halo, alkyl or alkoxy), or R.sub.1 is optionally alkylated carbamoyl;

Therapeutic agents

Therapeutic 1,4-thiazepines

Tetraisoquinoline compounds which have useful pharmaceutical utility

Compounds of formula I ##STR1## and pharmaceutically acceptable salts thereof; in which R.sub.1 and R.sub.2, which are the same or different, are H or an optionally substituted hydrocarbon group or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form an optionally substituted heterocyclic ring;

Arylcyclobutylmethylamine therapeutic agents

Arylcyclobutylmethylamines

Growing community of inventors

Nottingham, United Kingdom

Bruce Jeremy Sargent