University of Washington

Johns Hopkins University

Nlm Photonics

Bruce H Robinson

Lewis E Johnson

Delwin Elder

Huajun Xu

Luke Nathaniel Latimer

Rose Ann Cattolico

Zachary H Watanabe-Gastel

Larry R Dalton, Iii

William Robert Hardin

Thomas E Conturo

Scott R Hammond

Kevin M O'malley

Disclosed are organic electrooptic materials. The electrooptic materials are functionalized by novel methods and structures. The electrooptic materials are structured with a head and a tail where the head and tail sequentially assemble into a non-centrosymmetric ordered array. The electrooptic materials are further structured in covalently bonded dimer pairs where one of the pairs is zwitterionic. The non-centrosymmetric ordered array bonds directly to electrodes which allows for efficient application of the electric field. The organic electrooptic materials disclosed offer greater hyperpolarizability, greater bandwidth, reduced operating voltage with less optical loss.

Sequential synthesis technique for deposition of aligned organic electro-optic materials

Chromophores with large hyperpolarizabilities, films with electro-optic activity comprising the chromophores, and electro-optic devices comprising the chromophores are disclosed.

Organic electro-optic chromophores

Crosslinked films having electro-optic activity, compositions and compounds for making the films, methods for making the films, and devices that include the films are disclosed.

Crosslinkable nonlinear-optical chromophore system

Fluorescent dyes with affinity for nucleic acids and related methods are provided. Dielectric or semiconducting films including fluorescent dyes with affinity for nucleic acids and related methods are also provided. Coumarin-based surfactants conjugated to the fluorescent dyes with affinity for nucleic acids and related methods are provided.

Fluorescent dyes and related methods

Fluorescent dyes with affinity for nucleic acids and related methods are provided. Dielectric or semiconducting films including fluorescent dyes with affinity for nucleic acids and related methods are also provided. Coumarin-based surfactants conjugated to the fluorescent dyes with affinity for nucleic acids and related methods are provided. Fluorescent compounds capable of interacting with DNA can be used for a variety of applications.

A method of vector magnetic resonance measuring and imaging and associated apparatus provide for a specimen being placed in a main magnetic field, RF pulses being impinged thereon, and magnetic field gradients being superimposed thereupon, preferably with three input gradient pulses being impinged preferably simultaneously to construct a balanced system of four gradient vectors having equally strong moments Four cycles of such input gradient pulses are employed to create four magnetic gradient moments from which velocity or motion vectors are created. A receiver obtains signals from a specimen and converts them into information which is introduced into a computer. The computer converts the signals sensitized by the gradient vector moments into motional-type vector information which can be measured and imaged. Different approaches may be taken for low velocity and high velocity usages. In the latter case, as well as others, a null acquisition which does not substantially adversely affect the signal-to-noise ratio may be employed.

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Seattle, WA, United States of America

Bruce H Robinson