International Minerals & Chemical Corp.

Bruce D Burleigh

Richard E Ivy

Glen W Wolfrom

Edwin J Hamilton, Jr

Darla S Murphy

Growth hormones are admixed with various stabilizers to provide for the decreased formation of insolubles and preservation of the soluble bioactivity of the growth hormone in aqueous environments. Examples of such stabilizers include certain polyols, amino acids, polymers of amino acids having a charged side group at physiological PH, and choline salts.

Stabilization of growth hormones

Two different ionic forms of somatomedin C (pI 6.4-7.0 and pI 8.3-8.6) are separated and isolated by applying an aqueous solution of somatomedin C to a strong cation-exchange column, eluting the somatomedin C from the column by applying a salt concentration gradient at constant pH and recovering the two ionic forms in different eluant fractions.

Method for purifying and isolating two ionic forms of somatomedin C

A composition for promoting the growth or feed conversion efficiency of meat-producing animals which contains growth-promoting amounts of growth hormone and a zearalin.

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Mundelein, IL, United States of America

Bruce D Burleigh