Hill's Pet Nutrition, Inc.

University College Cardiff Consultants Limited

Bruce Caterson

Dennis Edward Jewell

William David Schoenherr

Dale Allen Fritsch

Christopher Bond Little

John Leander Harwood

John Francis Innes

Christopher McGuigan

Clare Elizabeth Hughes

Clare Louise Curtis

Antonella Carangio

A method for modulating enzymatic degradation of articular cartilage in a dog comprises administering to the dog an enzymatic degradation modulating effective amount of eicosapentaenoic acid (EPA), for example as a component of a food composition. By practice of the method in a dog having arthritis, mobility of the dog can be increased, weight bearing in an arthritic limb can be increased, and/or pain associated with arthritis can be reduced.

Method for decreasing cartilage damage in dogs

Methods for decreasing cartilage damage in dogs

The present invention provides a phosphoramidate compound having the structure (I) wherein X comprises a monosaccharide group comprising the structure (II) or (III) or a pharmaceutically acceptable salt, ester or salt of such ester. The present invention also provides processes for the production of (I) and uses thereof.

Phosphoramidate derivatives

Growing community of inventors

Cardiff, United Kingdom

Bruce Caterson