Life Technologies Corporation

University of Oregon

The Uab Research Foundation

University College Cardiff Consultants Limited

Morehouse School of Medicine

Life Technologies As

University of Pittsburgh

Complexa Inc.

Bruce Branchaud

Bruce A Freeman

Lai-Qiang Ying

Francisco Jose Schopfer

Yuqing E Chen

Paul Baker

Valerie O'Donnell

Steven Menchen

Geir Fonnum

Hee Chol Kang

Dmitriy Gremyachinskiy

Nini Kjus

Stephen T Yue

Eric Tulsky

Richard M Fike

Yu-Zhong Zhang

Eric Welch

Shawn Barrett

Imad Naasani

Roman Rozhkov

Ramesh Jasti

John Matthew Mauro

Curtis Colwell

Terri Lovell

Brittany White

Biotin derivatives, methods of using the biotin derivatives and kits comprising the biotin derivatives.

Biotin derivatives

Disclosed herein are embodiments of nanohoop compounds and conjugates thereof that can be used myriad biological applications. The nanohoop compounds described herein can exhibit beneficial properties that are useful in biotechnology, such as a fluorescent tag, probe, or label.

Nanohoop compounds for use in biotechnology and methods of making and using the same

Methods for increasing the stability of, or protecting, labile components such as ethanolamine, growth factors, vitamins, etc., in compositions such as a cell culture medium. Stability of the labile compound is increased either, by derivatization of the labile compound with chemicals, or by sequestering the labile compound. Sequestering can be done either by encapsulation within a microcapsule, or by the use of sequestering agents. Encapsulation includes the encapsulation of dendrimers complexes of susceptible compounds within the microcapsule, thereby providing the controlled release of the susceptible compound that was protected. These methods may improve and extend storage conditions of compositions comprising the labile compounds, improve shipping and handling of compositions comprising the labile compounds, such as dry media formulations, at room temperature rather than at lower temperatures thereby decreasing shipping costs. Stabilization of labile compounds in compositions such as dry format media can be viewed as a contribution to green technology.

Compositions and methods for stabilizing susceptible compounds

Methods for increasing the stability of, or protecting, labile components, such as ethanolamine, growth factors, vitamins, etc., in compositions such as a cell culture medium, are described. Stability of the labile compound is increased either, by derivatization or by sequestering the labile compound. Sequestering can be done either by encapsulation within a microcapsule or by the use of sequestering agents. Encapsulation can provide controlled release of the susceptible compound being protected. These methods may improve or extend the storage conditions, the shipping and handling of media compositions comprising the labile compounds at room temperature rather than at lower temperatures, thereby decreasing shipping costs.

Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Nitrated lipids and methods of making and using thereof

A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.

Hydrophobic diacrylamide compound

Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.

Vinyl substituted fatty acids

A nanoparticle having one or more phosphonates or phosphinate ligands on their surface can be converted into nanoparticles with sulfonate ligands on their surface, by contacting the phosphonate-containing nanoparticles with a silylsulfonate reagent. Such nanoparticles are activated toward reactions with nucleophilic groups; thus the method provides activated nanoparticles, and methods of making and using them to produce modified nanoparticles.

Sulfonate modified nanocrystals

Growing community of inventors

Eugene, OR, United States of America

Bruce Branchaud