Monteris Medical Corporation

Covidien LP

St. Jude Medical, Cardiology Division, Inc.

Aga Medical Corporation

Ev3 Inc.

Rg Innovation, LLC

Brooke Ren

Richard Tyc

Mark A Grant

Richard S Kusleika

Eric Andrews

Daniel O Adams

Thomas L Clubb

Cathleen Von Lehe

John C Oslund

Mathias Charles Glimsdale

Matthew Charles Heidner

James Lininger

Kurt Amplatz

Jason A Galdonik

Brian Joseph Perszyk

Patrick P Russo

Ryan Kariniemi

Chris Quinn

Sara Jane Gries

Carolyn Cochenour

Cheryl A Lecy

Thomas Clubb

Embodiments of the present invention provide medical devices and methods for treating a target site within the body. For example, one embodiment provides a stent graft for treating a target site proximate to a bifurcated lumen, wherein the stent graft includes a first tubular structure having proximal and distal ends and a side wall extending therebetween. The first tubular structure includes an opening defined within the side wall and is configured to define a first portion having first and second ends and a second portion having first and second ends. The opening corresponds to the first ends of the first and second portions and the second ends of the first and second portions respectively correspond to the proximal and distal ends of the first tubular structure, and at least a portion of the first and second portions are configured to be positioned within respective branches of a bifurcated lumen.

Bifurcated medical device for treating a target site and associated method

Embolic protection devices and systems capture and/or deflect emboli from entering one or more arterial branches of the aorta. An embolic protection device may include an anchor section that is positionable within an arterial branch of the aorta and a shield section that is operatively coupled to the anchor section. The shield section is positionable relative to one or more ostia of the aortic branches and is held in that position by the anchor section.

Embolic protection device

One exemplary device includes a tubular structure having proximal and distal ends and at least one layer of braided material configured to facilitate thrombosis. The tubular structure includes an end section at the proximal or distal end having a cross-sectional dimension that is larger than that of an opening of the target site. The device also includes a stiffener wire coupled to the tubular structure, and the wire is configured to extend at least partially through the opening and facilitate securing the end section over the opening. The tubular structure and stiffener wire include respective preset, expanded configurations and are configured to be constrained to respective reduced configurations for delivery to the target site and to at least partially return to their respective preset, expanded configurations at the target site when unconstrained.

Medical device with stiffener wire for occluding vascular defects

In an embodiment, a method for effecting thermal therapy using an in vivo probe includes positioning the probe in a volume in a patient, identifying an irregularly shaped three-dimensional region of interest and automatically applying thermal therapy to the region using the probe. Applying thermal therapy may include identifying a first emission level at a first rotational angle based in part on a depth of a radial portion of the region in the direction of probe emission, activating emission of the probe, causing rotation of the probe to a next rotational angle, identifying a next emission level at the next rotational angle based in part on a depth of a radial portion of the region in the direction of probe emission, activating emission to deliver therapeutic energy, and repeating rotation and emission until therapeutic energy has been delivered to the volume.

Automated therapy of a three-dimensional tissue region

An intravascular medical device including an elongated member configured to be advanced along a vascular path of a patient, the elongated member having opposite first and second ends, the first end and second ends both being adapted for intravascular insertion, and the first end having a different structure than the second end. The elongated member has sufficient flexibility to be advanced through a human vasculature. Preferably, the first and second ends are adapted to have different operating characteristics. Depending on the operating characteristics needed for a particular procedure, a physician can insert either the first end portion or the second end portion of the elongated member into the patient's vasculature.

Double ended intravascular medical device

In one aspect, the present disclosure relates to a head fixation apparatus including a number of support posts, and a curved ring portion including a number of connectors configured to adjustably and releasably mount support posts on the lower ring portion, such that the support posts are selectively mounted to a subset of the connectors in a customized arrangement for a patient. The apparatus may include a ring mount configured for fixation to a platform, including a curved channel substantially matching a curvature of the curved ring portion, and a mount locking mechanism for locking the curved ring portion within the channel of the ring mount. The curved ring portion may be configured to rotate within the channel of the ring mount while the ring mount is fixed to the platform, an angular head position of the patient being selectably adjustable while the patient is laying on the platform.

Image-guided therapy of a tissue

A variable length interstitial probe apparatus includes: a probe for effecting thermal therapy and/or cryotherapy to a tissue; a flexible umbilical sheath permanently affixed to the probe, including at least one interface for supplying energy, cooling fluid, cooling gas, heating fluid, and/or heating gas to the probe; and an adjustable depth stop configured to slide along a length of a shaft region of the probe, and lock to the shaft region at a selected position. The adjustable depth stop is configured to engage a probe driver and/or a skull mount apparatus to stabilize positioning of the probe and to control a depth of entry of the probe into a patient. The probe may be configured to effect temperature modulation therapy, where processing circuitry activates a modulation pattern of thermal therapy emission and cryogenic therapy emission for applying a thermal dose to the tissue.

Cryotherapy, thermal therapy, temperature modulation therapy, and probe apparatus therefor

Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an user of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser or high-intensity focused ultrasound probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

An embolic protection device comprising an expandable structure and a catheter. The catheter has a distal region and a working channel dimensioned to slideably receive an interventional device. The expandable structure is attached to the distal region of the catheter. The expandable structure has an expandable working channel extension and a working channel opening, the expandable working channel extension has a proximal end and a distal end, the proximal end of the working channel extension is attached to a distal end of the working channel, and the distal end of the working channel extension forms the working channel opening. The working channel opening is disposed proximate an exterior surface of the expandable structure when the expandable structure is expanded. The working channel, working channel extension, and the working channel opening form a continuous lumen.

Embolic protection systems

An embolic protection device includes an outer surface that is configured to form a substantially sealed relationship with a body lumen such that emboli are deflected and/or captured by the outer surface before such emboli can travel to other parts of the body. An inner surface of the embolic protection device includes a longitudinally extending lumen through which instrumentation may be inserted, facilitating passage of such instrumentation through the body lumen while minimizing risk to the patient from emboli.

Embolic protection pass through tube

A catheter that includes storage for an embolic protection device in an accessible, out-of-the-way location within the advancing catheter.

Holding zone for intravascular medical device

Image-guided therapy of a tissue can utilize magnetic resonance imaging (MRI) or another medical imaging device to guide an instrument within the tissue. A workstation can actuate movement of the instrument, and can actuate energy emission and/or cooling of the instrument to effect treatment to the tissue. The workstation and/or an operator of the workstation can be located outside a vicinity of an MRI device or other medical imaging device, and drive means for positioning the instrument can be located within the vicinity of the MRI device or the other medical imaging device. The instrument can be an MRI compatible laser or high-intensity focused ultrasound probe that provides thermal therapy to, e.g., a tissue in a brain of a patient.

The various embodiments disclosed herein relate to introducer sheaths having an expandable and retractable shaft configured to receive a positionable medical device therethrough. In some embodiments, the shaft is selectively expandable and retractable based on the position of the positionable device within the shaft.

Expandable introducer sheath and related methods

Thermal monitoring of tissue during a thermal therapy may include identifying an imaging plane bisection axis lying along at least one of a longitudinal axis of a thermal therapy instrument and a vector through a region of interest. The method may include identifying multiple thermal monitoring planes used in monitoring thermal therapy of the volume, where each thermal monitoring plane intersects the region of interest, where a first thermal monitoring plane intersects a second thermal monitoring plane at the imaging plane bisection axis, and the first thermal monitoring plane is offset from the second thermal monitoring plane by an angle of intersection. The method may include and performing thermal monitoring of the thermal therapy by obtaining magnetic resonance (MR) images obtained from the first monitoring plane and the second monitoring plane, and calculating, based on the images, temperature data of the volume.

Growing community of inventors

Maple Grove, MN, United States of America

Brooke Ren