3m Innovative Properties Company

Brinda Balasubramaniam Lakshmi

Charles M Leir

Karl E Benson

Rahul R Shah

Moses Mekala David

Cary A Kipke

George G I Moore

George G Moore

G Marco Bommarito

Albert I Everaerts

Peter A Stark

Lang N Nguyen

M Benton Free

John P Baetzold

Patrick A Mach

David R Holm

James Stephen Mrozinski

Jeffrey D Smith

John S Huizinga

Seth M Kirk

Todd W Johnson

Michael P Daniels

Brian Edward Spiewak

Dan L Fanselow

Jonathan F Hester

Larry H Dodge

Triet M Lu

Bathsheba E Chong Conklin

Jerald W Hall, Jr

Peggy-Jean P Flanigan

Angela K Dillow

George G I Moora

Dasaratha V Sridhar

George GI Moore

George G L Moore

Marco G Bommarito

Benton M Free

An apparatus assembly for detecting an analyte in a sample of material includes a valve, a frame, and a plurality of housing segments. The valve may be actuated to adjust a flow path and flow rate through the housing segments.

Apparatus and method for detecting an analyte

Compounds having two reactive functional groups are described that can be used to provide a connector group between a substrate and an amine-containing material. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonylaminocarbonyl group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a carbonylimino-containing connector group. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.

N-sulfonylaminocarbonyl containing compounds

Acoustic sensors, preferably surface acoustic wave sensors, and more preferably shear horizontal surface acoustic wave sensors that include soluble mixed with oligomers and/or polymers formed from such monomers), or multifunctional compounds, for example, that can function as either waveguide materials, immobilization materials for secondary capture agents (e.g., antibodies), or both.

Acoustic sensors and methods

Multifunctional compounds having acylsulfonamide amine-reactive groups are described that can be used for the capture of amine containing materials.

Multifunctional amine capture agents

Compounds having two reactive functional groups are described that can be used as a tethering compound to immobilize an amine-containing material to a substrate. The first reactive functional group can be used to provide attachment to a surface of a substrate. The second reactive functional group is a N-sulfonyldicarboximide group that can be reacted with an amine-containing material, particularly a primary aliphatic amine, to form a connector group between the substrate and the amine-containing material. The invention also provides articles and methods for immobilizing amine-containing materials to a substrate.

N-sulfonyldicarboximide containing tethering compounds

Articles and methods for the use of such articles are described for use in immobilizing nucleophile-containing materials. In one aspect, the invention provides an article comprising: a substrate having a first surface and a second surface; and a phosphonitrilic tethering group affixed to the first surface of the substrate, the phosphonitrilic tethering group comprising a reaction product of a complementary functional group on the first surface of the substrate with a phosphonitrilic tethering compound. A method of immobilizing a nucleophile-containing material to a substrate is also described, the method comprising: providing a phosphonitrilic tethering compound; providing a substrate having a complementary functional group capable of reacting with phosphonitrilic tethering compound; preparing a substrate-attached phosphonitrilic tethering group by reacting the phosphonitrilic tethering compound with the complementary functional group on the substrate resulting in an ionic bond, covalent bond, or combinations thereof; and reacting the substrate-attached phosphonitrilic tethering group with a nucleophile-containing material to immobilize the nucleophile-containing material.

Substrates and compounds bonded thereto

Soluble polymers and methods for the preparation thereof, wherein the polymers of the present invention have pendant acylsulfonamide amine-reactive groups that can be used for the capture of amine containing materials.

Soluble polymers as amine capture agents and methods

Articles and methods for the high-energy desorption/ionization of various compositions are disclosed. Methods of the invention utilize porous substrates, optionally in combination with one or more surface coatings and fillers, to provide enhanced desorption of analytes. Such enhanced desorption is particularly useful in fields of analysis such as mass spectrometry. This enhanced desorption has various utilities. For example, use of the porous substrate may allow desorption to be performed without the use of chemical matrices.

Method for laser desorption mass spectrometry using porous polymeric substrates with particle fillers

The invention relates to methods of detecting

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Growing community of inventors

Woodbury, MN, United States of America

Brinda Balasubramaniam Lakshmi