Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Sante Et Humaines S.e.c.

Brigitte Guerin

Fernand Gobeil

David Fortin

Martin Lepage

Sebastien Tremblay

Samia Ait-mohand

Robert Sabbagh

Aiman H Alnahwi

The present disclosure relates processes and systems for producing and/or purifyingGa from an irradiated substrate ofZn. In some embodiments, the process rely on the use two cation-exchange chromatography columns to separateGa fromZn and other radionuclides and metallic impurities. The process achieves a high overall yield ofGa and a high effective molar activity while being implementable in a time compatible with the short half-life ofGa. In additional embodiments, the process is implemented by an automated system.

Processes and systems for producing and/or purifying gallium-68

It is provided new chemical entities allowing simultaneous diagnosis and treatment of cancers. More specifically, it is provided a theranostic compound consisting of a stabilized peptide ligand (agonists and antagonists) for the kinin B1 receptors (B1R) conjugated to specific radionuclides (e.g.Cu) suitable for dual imaging/radiotherapy applications.

Kinin-based theranostic probes for solid cancers and uses thereof

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Sherbrooke, Canada

Brigitte Guerin