Rhone-poulenc Sante

May & Baker, Ltd.

Brian W Sharp

Terance W Hart

Bernard Yvon Vacher

Dennis Warburton

Roger J Walsh

Kenneth Robert Wooldridge

Malcolm N Palfreyman

David C Cook

Raymond Barry Williams

Jack Hill

By Thomas Walker, Administrator

Iain M Mc Lay

Robert B Walker, Deceased

Thioformamide derivatives of the formula (I) ##STR1## wherein R represents an alkyl group; A represents either:

Thioformamide derivatives

Therapeutically useful thioformamide derivatives of the formula: ##STR1## wherein R represents alkyl, Het represents pyrid-3-yl, isoquinolin-4-yl, tetrahydroquinolin-3-yl, quinolin-3-yl, pyridazin-4-yl, pyrimid-5-yl, thiazol-5-yl, thieno[2,3-b]-pyridin-5-yl, pyrazin-2-yl, indol-3-yl and thieno[3,2-b]-pyridin-6-yl, Y represents ethylene, methylene or a valency bond, and X represents carbonyl, hydroxymethylene, &gt;C.dbd.NOR.sup.1, &gt;C.dbd.NN(R.sup.1).sub.2 or &gt;C.dbd.NN(R.sup.1)CON(R.sup.1).sub.2 in which R.sup.1 represents hydrogen or optionally substituted alkyl, benzyl, phenethyl, 1-naphthylmethyl, 2-naphthylmethyl or pyrid-3-ylmethyl, or two R.sup.1 substituents on the same nitrogen atom may together form an optionally substituted alkylene radical chain and salts thereof, processes for their preparation and compositions containing them are described.

Derivatives of thioformamide

This invention relates to a thioformamide derivative of the formula I ##STR1## wherein: R and R.sup.1 each independently represent an alkyl group;

Pyrid-3-yl thioformamide compounds which have useful pharmaceutical

Compounds of the formula: ##STR1## wherein R.sup.1 represents a methyl or ethyl group, R.sup.2 represents a bromine or chlorine atom, and R.sup.3 represents a hydrogen, chlorine, bromine or iodine atom, an alkyl or alkenyl group containing up to 4 carbon atoms, or a cyano or trifluoromethyl group, are new compounds possessing antimalarial properties.

Pyrimidine derivatives

Compounds of the formula: ##SPC1## Wherein R.sup.1 represents hydrogen, methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl or sec-butyl, R.sup.2 represents hydrogen or alkyl of 1 through 4 carbon atoms or cycloalkyl of 3 or 4 carbon atoms, and R.sup.3 represents hydrogen, methyl or ethyl, all of which are novel except for three compounds, have been found to be of use in the prevention of coccidiosis in chickens.

Method of preventing coccidiosis with 3,5-dinitroaniline derivatives and

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Hornchurch, United Kingdom

Brian W Sharp