Pall Corporation

Brian T Muellers

David B Pall

Thomas C Gsell

Peter J Degen

Tony Alex

Michael R Gildersleeve

A method for bonding a porous medium to the surface of a solid substrate is disclosed. The method comprises contacting a dry porous medium with a dry surface of a substrate and impregnating the porous medium with a bonding composition. The impregnated porous medium is maintained in contact with the substrate surface until the substrate surface is at least slightly dissolved in the bonding composition without dissolving the porous medium. At least a portion of the bonding composition is flushed through the impregnated porous medium towards the substrate and subsequently away from the surface of the substrate. The bonding composition is then evaporated at a controlled rate from the substrate and the porous medium.

Method for bonding a porous medium to a substrate

Composite structure having a porous filter medium and a method for

A method for preparing platelets comprises the steps of obtaining whole blood from human, preparing platelet rich plasma from the whole blood and then passing the platelet rich plasma through a filter comprising a porous medium having a CWST of at least about 70 dynes/cm, under conditions sufficient to remove in excess of about 99.99% of the leucocytes from the platelet rich plasma, with preparing platelet rich plasma and passing the platelet rich plasma through the filter occurring in an integrally-attached blood bag system within a few hours of obtaining whole blood from human.

Method for preparing platelets

A device for processing donated blood comprises a porous medium interposed between the collection bag and a satellite bag into which a component separated by centrifugation can be expressed, the filter element preferably having a CWST of about 70 to about 115 dynes/cm. The porous medium blocks red blood cells, but allows platelets to pass therethrough.

Method for processing blood for human transfusion

A method for bonding a porous medium to a substrate is provided which includes contacting a porous medium with a surface of a substrate, impregnating the porous medium with a bonding composition, maintaining the impregnated porous medium in contact with the substrate surface until the substrate surface is at least slightly dissolved in the bonding composition without dissolving the porous medium, and passing the bonding composition through the impregnated porous medium towards the substrate and subsequently away from the surface of the substrate to remove bonding composition containing dissolved substrate from a portion of the porous medium to minimize blockage of pores in the porous medium.

Device and filter element for processing blood for human transfusion

A method of preparing platelets for long term storage comprises the steps of (a) obtaining whole blood from a human, (b) preparing platelet rich plasma from the whole blood and (c) then passing the platelet rich plasma through a filter under conditions sufficient to remove substantially all leucocytes from the plasma, with steps (b) and (c) occurring in an integrally attached blood bag system within a few hours of step (a).

Device for processing blood for human transfusion

The invention discloses a method for treating blood comprising (a) centrifuging blood and (b) passing a supernatant layer of the centrifuged blood through a porous medium until red blood cells block the porous medium.

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Rockville Centre, NY, United States of America

Brian T Muellers