Vertex Pharmaceuticals, Inc.

Curt G. Joa, Inc.

Brian R Krueger

Fredrick Van Goor

Gregor Zlokarnik

Adam R Looker

Martin Trudeau

John A DeMattei

Martyn Botfield

Stefanie Roeper

Bobbianna Neubert-Langille

Michael P Ryan

Peter D J Grootenhuis

Dahrika Milfred Yap Guerette

Fredrick F Van Goor

Dahrika Milfred Yap

Martyn C Botfield

John Demattei

Peter D Grootenhuis

Chris Lee Nelson

Robert E Andrews

Peter Diederik Jan Grootenhuis

Jeffrey Wayne Fritz

Adam D DeNoble

Alan J Rabe

Peter Dj Grootenhuis

Dahrika Milfred Lao Yap

Stefanie Roper

Peter DJ Grootenhuis

Bobbiana Neubert-Langille

Frederick F Van Groor

Adam D Denoble

Chris J Nelson

Frederick F Van Goor

A temperature probe holder is provided. The device includes a magnetic fastener and a probe clip, whereby a connector secures the probe clip to the magnetic fastener. The magnetic fastener includes a notch and a slot. The probe clip includes a pair of resilient arms that extend upwardly and outwardly at opposite angles from a central base. Each resilient arm includes coaxially aligned apertures, such that a temperature probe can be inserted through a pair of coaxially aligned apertures. The temperature probe is secured to the probe clip due to an outward angle of the pair of resilient arms at rest. In operation, the magnetic fastener engages any ferromagnetic section of a cooking device. The device allows users to easily secure a temperature probe to various surfaces inside a cooking device. In some embodiments, the magnetic fastener is secured to an elongated ceramic bar.

Temperature probe holder

The invention provides a process for the preparation of a compound of Formula 1, comprising coupling a carboxylic acid of Formula 2 with an aniline of Formula 3 in the presence of a coupling agent.

Process for making modulators of cystic fibrosis transmembrane conductance regulator

Apparatus and methods are provided to minimize waste and improve quality and production in web processing operations. The apparatus and methods provide defect detection both before and after application of component patches to a traveling web to create a product. Web defect detection may be provided by way of at least one visual inspection station located upstream from the patch applicator. Patch defect detection may be accomplished by way of a visual inspection station located proximate the patch applicator. If defects are detected in either the traveling web or the component patch prior to patch application, patch application may be prevented until both a satisfactory web and patch are provided. If defects are detected after patch application, the resulting product may be culled. Furthermore, the apparatus may be provided with diagnostic software to warn against extant or imminent machine complications.

Apparatus and method for minimizing waste and improving quality and production in web processing operations

Growing community of inventors

Cambridge, MA, United States of America

Brian R Krueger