Pacesetter, Inc.

Siemens-pacesetter, Inc.

Cedars-sinai Medical Center

Pacesetter Systems Inc.

Other

Savacor, Inc.

Brian M Mann

Neal L Eigler

James S Whiting

John W Poore

Paul A Levine

Jason A Sholder

Werner Hafelfinger

Melinda A Endaya

Jeffery D Snell

Joseph J Florio

Roy B Medlin

Gene A Bornzin

Allan R Schwartz

Harold C Schloss

Stuart W Buchanan

Laurence S Sloman

Russell R Beane

James D Causey, Iii

Leslie S Miller

Bruce L Wilkoff

Joseph H Schulman

Kelly Hobart McClure

John L Wardle

Phong D Doan

Wayne A Morgan

Herman Lee Renger

Kenneth Valikai

Xiangqun Chen

John T Meador

Min-Yaug Yang

Gregory C Bevan

David W Adinolfi

Raymond J Wilson

J Kelly Fox

Jonathan A Kleks

Azita M Rahbari

Marc I Hurowitz

Hakan Hornell

This invention relates generally to systems and methods for optimizing the performance and minimizing complications related to implanted sensors, such as pressure sensors, for the purposes of detecting, diagnosing and treating cardiovascular disease in a medical patient. Systems and methods for anchoring implanted sensors to various body structures is also provided.

Implantable pressure transducer system optimized to correct environmental factors

A method of treating cardiovascular disease in a medical patient is provided. The method includes the steps of generating a sensor signal indicative of a fluid pressure within the left atrium of the patient's heart, and delivering an electrical stimulus to a location in the heart. The electrical stimulus is delivered based at least in part on the sensor signal. The method also includes the steps of generating a processor output indicative of a treatment to a signaling device. The processor output is based at least in part on the sensor signal. At least two treatment signals are provided to the medical patient. The treatment signals are distinguishable from one another by the patient, and are indicative of a therapeutic treatment. The treatment signals are based at least in part on the processor output.

Method for detecting, diagnosing, and treating cardiovascular disease

This invention relates generally to systems and methods for optimizing the performance and minimizing complications related to implanted sensors, such as pressure sensors, for the purposes of detecting, diagnosing and treating cardiovascular disease in a medical patient. Systems and methods for anchoring implanted sensors to various body structures are also provided.

Implantable pressure transducer system optimized for reduced thrombosis effect

A method of monitoring pressure within a medical patient, includes measuring an actual pressure in a medical patient in a first time period; measuring an indicator of the actual pressure in the first time period, wherein the indicator is derived from an electrical signal of the patient's heart; determining a correlative relationship between the actual pressure and the indicator, wherein both the actual pressure and the indicator are obtained in the first time period; measuring the indicator in a second time period; and determining the actual pressure in the second time period based on the correlative relationship obtained in the first time period and the indicator obtained in the second time period.

Hemodynamic waveform-based diagnosis and treatment

A method for accessing a target site in the body by transferring a guidewire from an initial insertion site on the body to a different insertion site on the body is provided. In one aspect, a method for transferring a medical device or component, such as a sensor lead, from an initial insertion site to another insertion site is also provided. A guidewire of sufficient length, pliancy and deformability to perform a transfer from one insertion site to another insertion site is provided. In one aspect, the guidewire comprises a removable core mandrel to increase rigidity, facilitate insertion and/or improve steerability. A kit or system, comprising introducers, guidewires and catheters for performing a guidewire or device transfer is also provided.

System and method for manipulating insertion pathways for accessing target sites

A cardiac rhythm management apparatus includes a proximal housing, a distal housing and a lead. The proximal housing includes a first energy storage device. The distal module is implantable within a patient's heart, and includes a second energy storage device, at least one electrode, and a control module. The control module controls the delivery of at least one electrical stimulus from the second energy storage device to a location in communication with the patient's heart. The lead connects the proximal housing to the distal module and is configured to communicate one or more digital signals between the proximal housing and the distal module.

Method for digital cardiac rhythm management

Embodiments include a cardiac rhythm management system having a lead that includes an omni-directional pressure sensor that is configured to resist tissue in-growth and provide reliable and consistent pressure readings from within a patient's vasculature. Embodiments of the cardiac rhythm management lead may also include a variety of pacing and shocking electrodes.

Cardiac rhythm management lead with omni-directional pressure sensing

Method for estimating cardiac pressure using parameters derived from impedance signals detected by an implantable medical device

Systems and methods for penetrating a tissue membrane to gain access to a target site are disclosed. In some examples, systems and methods for accessing the left atrium from the right atrium of a patient's heart are carried out by puncturing the intra-atrial septal wall. One embodiment provides a system for transseptal cardiac access that includes a stabilizer sheath having a side port, a shaped guiding catheter configured to exit the side port and a tissue penetration member disposed within and extendable from the distal end of the guide catheter. The tissue penetration member may be configured to penetrate tissue upon rotation and may be coupled to a distal portion of a torqueable shaft. In some embodiments, the stabilizer sheath and shaped guiding catheter may be moved relative to the patient's body structure and relative to each other so that a desired approach angle may be obtained for the tissue penetration member with respect to the target tissue.

Transmembrane access systems and methods

This invention relates generally to apparatus and methods for the calibration of implanted pressure transducers. It is an object of several embodiments of the present invention to provide apparatus and methods for the calibration of one or more implanted pressure transducers implanted in the body of medical patients. Various embodiments of the present invention are particularly advantageous because they offer a calibration system that is less invasive than the systems currently available.

Apparatus for minimally invasive calibration of implanted pressure transducers

System for detecting, diagnosing, and treating cardiovascular disease

System for calibrating implanted sensors

Patient signaling method for treating cardiovascular disease

Growing community of inventors

Beverly Hills, CA, United States of America

Brian M Mann