Glaxo Laboratories Limited

Brian M Bain

Gordon H Phillipps

John Colin Clark

The specification describes anti-inflammatory steroids having the following formula ##STR1## wherein X represents a hydrogen or fluorine atom, R' represents a methyl, ethyl, n-propyl or iso-propyl group, R' represents a methyl, chloromethyl, fluoromethyl, bromomethyl or 2-fluoroethyl group and represents a single or double bond. The specification describes processes for preparing such compounds as well as pharmaceutical compositions containing the compounds.

Pharmaceutical compositions of

The specification describes new anti-inflammatory steroids having the formula ##SPC1## Wherein R.sup.1 represents a C.sub.1-4 alkyl or halo- C.sub.1-4 alkyl group, R.sup.2 represents a methyl, ethyl, n-propyl or iso-propyl group (an ethyl group being especially preferred), X represents a hydrogen, chlorine or fluorine atom and -- represents a single or double bond. The specification describes processes for the preparation of such compounds as well as pharmaceutical compositions containing these compounds.

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Chalfont St. Peter, United Kingdom

Brian M Bain