Nexisvision, Inc.

Journey1, Inc.

Lifescan IP Holdings, LLC

Brian Levy

Cary J Reich

Eugene De Juan, Jr

Yair Alster

Matt Clarke

Kuangmon Ashley Tuan

Ashley Tuan

Douglas Sutton

Dean F Carson

Enrique Barragan

Doug Rimer

Jose D Alejandro

Raymond Lum

K Angela Macfarlane

K Angela MacFarlane

Angela K MacFarlane

Matt Clark

Kunagmon Ashley Tuan

Bovornrat K Cochard

David Shearer

Allison Gonzales

Mark Hofmeister

Lisa Troncelliti

Eugene De Juan

Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include a deformable inner portion and a deformable peripheral portion. When disposed over the optical region of an eye, the inner portion is configured so that engagement of the posterior surface against the eye deforms the posterior surface so that the posterior surface has a shape diverging form the refractive shape of the epithelium when viewing with the eye through the ophthalmic lens. The rigidity of the inner portion is greater than the rigidity of the peripheral portion and the ophthalmic lenses are configured to allow movement relative to the eye upon blinking of the eye and to be substantially centered on the optical region of the cornea following the blinking of the eye. Methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses are also disclosed.

Contact lenses for refractive correction

Systems, methods and graphical user interfaces for visualizing analyte measurements using animation are presented. For instance, a system for continuously monitoring analyte concentration in a physiological fluid includes a sensor, a transmitter, at least one processor and a display. The display is for outputting a graphical user interface. The display is controlled by the at least one processor to display, using the graphical user interface, historical analyte concentration levels and a trend indication animation. The trend indication animation comprises at least one visual element configured by the at least one processor to have a periodic motion between a first position and a second position on the display in one of a plurality of trend directions. The trend direction of the periodic motion between the first and second positions indicates whether the analyte concentration is increasing or decreasing and the rate of change of the analyte concentration level. The at least one visual element is further configured with a period of the periodic motion between the first and second positions in order to indicate a severity of an excursion of the analyte concentration.

Methods and devices for visualizing analyte measurements

A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1&#xd7;10&#x2212;4 Pa*m3 to about 5&#xd7;10&#x2212;4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.

Conformable therapeutic shield for vision and pain

A method for providing faster visual and functional recovery of patients following refractive surgery such as laser assisted in situ keratomileusis (LASIK) is disclosed. The method comprises providing a covering to the eye of a patient comprising an inner portion having an inner rigidity and at least one inner radius of curvature; and an outer portion having an outer rigidity and at least one outer radius of curvature; wherein the inner rigidity is greater than the outer rigidity.

Eye covering and refractive correction methods for lasik and other applications

Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include an inner optic portion configured to be disposed over the optical region of the cornea and having a central portion disposed between an anterior portion and a posterior portion. The inner optic portions configured to at least partially diverge from the shape of the cornea to provide at least one lenticular volume between a posterior surface of the inner optic portion and the cornea. The central portion may be characterized by a thickness from 50 &#x3bc;m to 900 &#x3bc;m and a modulus form 20 MPa to 1500 MPa.

Bimodular contact lenses

A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1&#xd7;10-4 Pa*m3 to about 5&#xd7;10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.

An eye covering such as a contact lens may comprise one or more structures to pump tear liquid under the covering such that the covering can remain in the eye and correct vision for an extended amount of time. In many embodiments, the covering comprises a material having fenestrations to draw tear liquid under the covering and an outer portion shaped to contact the conjunctiva over the sclera, such that when the eye closes pressure of one or more eyelids urges tear liquid through one or more fenestrations and under the outer portion shaped to contact the conjunctiva. When the eye blinks, the pressure of the one or more eyelids can urge the covering toward the cornea such that tear liquid can pass through the fenestrations.

Eye covering and refractive correction methods and apparatus having improved tear flow, comfort, and/or applicability

Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include an inner optic portion configured to be disposed over the optical region of the cornea and having a central portion disposed between an anterior portion and a posterior portion. The inner optic portion is configured to at least partially diverge from the shape of the cornea to provide at least one lenticular volume between a posterior surface of the inner optic portion and the cornea. The central portion may be characterized by a thickness from 50 &#x3bc;m to 900 &#x3bc;m and a modulus form 20 MPa to 1500 MPa.

Methods and apparatus can fit coverings to treat eyes. The covering can be identified so as to provide improved flow of tear liquid under the covering. The covering can be identified based on an inner corneal curvature and an outer corneal curvature and one or more of a limbus sag height or a conjunctival sag height. The covering may form a chamber when placed on the eye to pump tear liquid under at least a portion of the covering. The covering may comprise an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The covering may comprise a material having high oxygen permeability, for example silicone, with a wettable coating disposed on at least an upper surface of the coating.

Growing community of inventors

New York, NY, United States of America

Brian Levy