Kimberly-clark Worldwide, Inc.

Tyco Healthcare Group LP

Avent, Inc.

Covidien LP

University of Florida Research Foundation, Incorporated

Brian Joseph Cuevas

Joshua Benjamin Stopek

Michael Z Sleva

Frank R Schiretz

Ahmad Robert Hadba

Joseph A Cesa

John Gavin MacDonald

Ramanathan S Lalgudi

Scott M Teixeira

Adrienne A Hershey

Joe Cesa

Sam C Chan

Marjory J Greenhalgh

David William Koenig

Alison Salyer Bagwell

Joseph Hotter

Stephen Avedis Baratian

Stephanie Kute

James F Schumacher

Frank J Viola

Thomas Wenchell

Ali Yahiaoui

Mark S Roby

Matthew D Cohen

Andrew Thomas Baker

Kelly Dean Branham

Jeffrey Eldon Fish

Brian F Nentwick

Phillip A Schorr

Jason Lye

Nadya Belcheva

Charles Alan Seegert

Robert DeSantis

Anthony Stephen Spencer

John J Kennedy

Anthony B Brennan

Michael Prescott

Robert J Cain

Charles Edward Bolian, Ii

James Frederick Schumacher

Michael A Kenowski

Andrew Sweeney

Molly K Smith

Kok-Ming Tai

Melissa S Roshon

Benone Tarcau

Ryan Clinton Frank

Sophie Truc Lam

Allison Salyer Bagwell

Karien J Rodriguez

Nathan G Bonn-Savage

Amy G Williams

Brian M Hatcher

Ali Irfan

Steven Tsai

Reade Harpham

David James McNamara

Ryan C Frank

Marjory Greenhalgh

Frank Richard Schiretz

John Gavin Macdonald

Stephen A Baratian

Phillip Andrew Schorr

Andrew V Sweeney

A wound dressing system that includes a conformal cover and an infusion pump is provided. The cover includes a fluid port and an oxygen catalyst. The infusion pump is configured to deliver a bioactive liquid to the cover via the fluid port. The liquid includes an oxygen precursor. Upon combination, the oxygen catalyst and precursor react to form oxygen. A method of applying a wound dressing system including a bioactive powder, a bioactive liquid, and a conformal cover to a wound site is also provided. The method includes applying the powder to the wound site; securing the cover around the wound site, where the cover includes an oxygen catalyst and a fluid port; and delivering the bioactive liquid to at least an inner layer of the cover via the fluid port, where the bioactive liquid includes an oxygen precursor.

Traumatic wound dressing system with conformal cover

A wound dressing system comprising a wrap and a frangible ampoule is provided. The wrap is configured to contact/surround a wound site and includes an oxygen catalyst. The ampoule includes an oxygen precursor. The catalyst and precursor are configured to form oxygen when combined. A wound dressing system including a container is also provided that includes a powder, wrap, and frangible ampoule. The powder is disposed within the container, which is configured to allow the powder to be dispersed onto a wound site when activated. The wrap, which may include an oxygen catalyst, is also disposed in the container and is configured to contact/surround the wound site. The ampoule, also disposed in the container, includes a liquid containing an oxygen precursor. The liquid is configured to contact the wrap when the container is activated. Further, the catalyst and precursor are configured to form oxygen when combined.

Traumatic wound dressing system with wrap

There is provided a composition comprising covalently linked segments of for example, polycaprolactone and polyethylene glycol that are linked by a cross-linker. Such a composition foams in the presence of a catalyst and a solution containing an oxygen forming chemical like hydrogen peroxide. The foamed composition retains oxygen for delivery to, for example, a wound, where it aids in healing.

Foams for oxygen delivery to wounds

A subglottic suctioning system with a tracheal tube having a ventilation lumen, a cuff inflation lumen, and a suction lumen are disclosed which may help reduce the incidence of ventilator associated (or acquired) pneumonia. The suction lumen communicates with the space in the trachea above the cuff where secretions accumulate. The suction lumen has a valve on the proximal end for connection to a source of vacuum. The valve is adapted to interrupt the supply of vacuum to the suction lumen to allow for the introduction of a rinsing fluid in its place and to automatically re-establish the connection to the source of vacuum upon completion of rinsing. The rinsing fluid aids in maintaining an open suction lumen and may include medicaments and mucolytic agents to enhance or promote healing or to alter the properties of the mucus to make removal easier. The user may easily and repeatedly alternate suction and rinsing fluid through the suction lumen, i.e., the user may 'pulse' the line to loosen, break up and remove secretions and deposits that may partially or completely block or clog the suction lumen.

Subglottic suctioning system

Novel biodegradable compositions are disclosed. The biodegradable compositions include at least one hydroxyl-terminated component and at least one bioactive peptide in a linear chain. The compositions may be utilized as medical devices including drug delivery devices, tissue adhesives and/or sealants.

Biodegradable peptide releasing polymers

There is provided a device for sampling bodily fluids. Some embodiments have a handle, a lumen, and a diverter valve. The distal end of the handle is adapted to connect with a sampling device and is in fluid communication with the lumen. There is a vacuum connection on the proximal end of the handle that is also in fluid communication with the lumen. A suction valve may desirably be located in the lumen to control the application of vacuum from the vacuum connection to the sampling device. The diverter valve directs the flow through the lumen such that a sample from the patient goes into a sputum trap when the trap is connected. The device may further have a saline port in fluid communication with the lumen, located distal to the suction valve, for rinsing the tube and diluting secretions.

System and method for sampling device for bodily fluids

The present disclosure relates to compositions comprising a copolymer that includes a first monomer and a second monomer that is different from the first monomer, wherein both the first and second monomer are selected from the group consisting of 3-sulfopropyl acrylate potassium salt, sodium acrylate, N-(tris(hydroxyl methyl)methyl)acrylamide, and 2-acrylamideo-2-methyl-1-propane sulfonic acid. The present disclosure further relates to methods for preparing the copolymer compositions and shaped articles comprising the copolymers.

Water-swellable copolymers and articles and coatings made therefrom

There is provided a balloon cuffed tracheostomy tube with a balloon designed so as to enhance the tube's anchorability without sealing the tracheal stoma. The tracheostomy tube device includes a conventional curved hollow tube. The distal end of the tube is adapted for insertion through a tracheal stoma and into the tracheal lumen of a patient's throat. The device further includes an inflatable balloon enveloping a portion of the tube. The balloon has a distal portion substantially centered about and attached to the distal end portion of the tube. The balloon also has a proximal portion attached to the bend region of the tube and positioned substantially off-center relative to the proximal portion of the tube and about the bend region below the proximal plane of the device. Upon inflation, this configuration provides for expansion of the balloon around the distal end portion of the tube and the proximal end portion of the tube below the proximal plane of the device to seal the trachea below the tracheal stoma and to avoid sealing the trachea above the tracheal stoma. This configuration of the balloon should allow secretions to exit the stoma so that they do not accumulate and become a possible source of ventilator acquired pneumonia.

Balloon cuff tracheostomy tube

Anti-fouling treatments are applied to polymer substrates for preventing bacterial adhesion. The polymer substrate may comprise a medical device, such as a catheter. The treatment generally comprises a polymer layer graft polymerized to the surface of the polymer substrate. An anti-biofilm agent is contained in the polymer layer or applied to the surface. A polymer over-layer is then applied that encapsulates the anti-biofilm agent. The anti-biofilm agent prevents bacterial adhesion through the polymer over-layer.

Endotracheal tubes and other polymer substrates including an anti-fouling treatment

A bioactive sol-gel solution includes a biocompatible polymer, a gelable inorganic base material, and at least one calcium and phosphorous molecular species. The base material can be an alkoxide, such as TEOS. The polymer acts as a viscosity modifier to the sol or gel, increases the viscosity range over which fibers can be sprayed or spun, and broadens the time period over which fibers can be sprayed or spun. A bioactive glass composite can be formed from the bioactive sol-gel solution, including a fibrous form. Fibers can serve as a scaffold for cell growth and in the repair of hard or soft tissue defects.

Sol-gel derived bioactive glass polymer composite

The present disclosure describes a coating for a surgical filament including a vinyl lactam polymer and a lactone polymer.

Coated filaments

There is provided a method for performing a tracheotomy. In this method a tracheostomy dilator has a body and a tip which are detachably attached. The tip has a proximal inner portion which is within the body while the tip is attached to the body. The dilator is inserted into the trachea and used to dilate an opening. After the trachea has been dilated, the body may be detached and removed from the tip, the tip remaining partially in the trachea. A dilator loading catheter installed within a tracheostomy tube may be mated with the tip and the tip, loading catheter and tracheostomy tube moved into the trachea. After the tracheostomy tube is installed, the tip and loading catheter may be withdrawn through the tracheostomy tube and the tracheostomy tube placed in service.

Method of performing a tracheostomy

The present disclosure relates to compositions comprising a copolymer that includes a first monomer and a second monomer that is different from the first monomer, wherein both the first and second monomer are selected from the group consisting of 3-sulfopropyl acrylate potassium salt, sodium acrylate, N-(tris(hydroxyl methyl)methyl)acrylamide, and 2-acrylamide-2-methyl-1-propane sulfonic acid. The present disclosure further relates to methods for preparing the copolymer compositions and shaped articles comprising the copolymers.

Growing community of inventors

Cumming, GA, United States of America

Brian Joseph Cuevas