Charles River Laboratories, Inc.

Reametrix Inc.

New Product Development Concepts LLC

Scranton Products, Inc.

Brian J Kolonia

Robert K Kolonia

Bala S Manian

Norman R Wainwright

Eric Stimpson

Robert A Kolonia

Victor Alunni

A swivel mount assembly for securing a device to a support element is presented. The assembly includes arm, ball portions, and collar. The arm has an exterior surface. Each ball portion includes a center portion with outer and inner surfaces bounded by sides disposed between ends and a flange portion extending outwardly from each side. The collar includes faces separately disposed within an aperture with a socket along each face. Each socket includes a surface extending into the collar at the face. The arm is disposed between the ball portions. The inner surface of each ball portion engages the arm. The outer surface of each ball portion engages one socket. The arm is swivelable with respect to the collar. The flange portions of one ball portion are moveable with respect to the flange portions of other ball portion. The flange portions limit rotation of the ball portion within the socket.

Swivel mount assembly

A telescoping syringe suitable for use with medications and other materials is presented. The telescoping syringe includes a valve, a plunger, and a barrel. The valve further includes a barrier, an outlet(s) through the barrier, and an annular extension extending from the barrier. The plunger further includes an inlet(s) and a first side wall with a proximal wall. The barrel includes a second side wall with a distal wall at one end and an open end at another end. The plunger is extendable from and retractable into the barrel at the open end via slidable engagement between first and second walls. The valve directly contacts one end of the first wall so that an annular flange slidingly engages an annular groove. The valve and the barrel slidingly contact the plunger so as to open and to close the inlet(s) and/or the outlet(s). The inlet(s) in the open position permits gas to enter a first reservoir within the plunger as fluid is transferred from the first reservoir through the outlet(s) in the open position to a second reservoir within the barrel.

Telescoping syringe with one-way valve

The invention relates to a porous planar cell capture system for use in determining the presence and/or amount of cells, for example, viable cells, in a liquid sample, and to methods of using such a cell capture system. The cell capture system contains a fluid permeable, planar membrane adopted to retain cells thereon, a fluid permeable support member that supports the membrane, and an optional register associated with the membrane.

Porous planar cell capture system and method of use

A modular latch bar is formed from a first segment that is configured to be connected to a locker handle and one or more extension segments which are attached to the first segment. One of the segments has an elongated body having a front surface, a back surface, a first end and a second end; and a T-shaped locking tab extending from the first end. Another segment has an elongated body having a front surface, a back surface, a first end and a second end. This segment has a T-shaped recess on the back surface. The T-shaped recess is sized and configured to receive the T-shaped locking tab and create a friction fit between the T-shaped locking tab and segment having the T-shaped recess. A post may be provided in the recess that fits into a hole in the T-shaped locking tab to provide a snap fit connection.

Modular latch bar

A telescoping syringe suitable for use with medications and other flowable materials is presented. The telescoping syringe includes a one-way valve, a plunger, and a barrel. The valve includes a barrier, an outlet(s) through the barrier, and an annular extension extending from the barrier. The plunger includes an inlet(s) and a proximal wall fixed at one end of a first side wall. The valve directly contacts a distal end of the first wall so that an annular flange extending inward from the annular extension slidingly engages an annular groove along the first wall between first and second positions. The circumferential end of the first wall contacts the barrier in the first position to close the outlet(s). The circumferential end does not contact the barrier in the second position to open the outlet(s). A first reservoir is defined by the first wall, the proximal wall, and the valve. The inlet(s) permits gas to enter the first reservoir as fluid is transferred through the valve to a second reservoir. The barrel includes a second side wall with a nipple fixed to a distal wall at one end and an open end at another end. The plunger is extendable from and retractable into the barrel at the open end via slidable engagement between first and second walls. The second reservoir is defined by the distal wall, the second wall, and the valve.

Porous planar cell capture system

A telescoping syringe suitable for use with medications and other ejectable or injectable fluids is presented. The syringe includes a plunger, a barrel, and a valve. The plunger is extendible from and retractable into the barrel. The plunger defines a first reservoir. The barrel defines a second reservoir as the plunger is extended from the barrel. The valve is disposed at one end of the plunger adjacent to a nipple extending from the barrel. A first sealing interface is formed by the valve and a distal wall along the barrel adjacent to the nipple. A second sealing interface is formed by an annular flange along the one-way valve and an annular groove along the plunger. A third sealing interface is formed by the valve and a circumferential end along the plunger. The sealing interfaces are closed prior to extension of the plunger from the barrel thereby preventing a gas from entering and a fluid from existing the first reservoir. The sealing interfaces are open when the plunger is extended from the barrel so that the gas enters the first reservoir via an inlet(s) along the annular groove and fluid is communicated into the second reservoir via an outlet(s) along the valve. The second and third sealing interfaces are closed when the plunger is retracted into the barrel thereby allowing fluid to exit the second reservoir via the nipple.

The invention relates to a method for determining the presence and/or amount of viable cells in a liquid sample. The method includes (a) labeling with a fluorescent label viable cells remaining on a porous membrane after passing the liquid sample therethrough, (b) scanning a portion of the porous membrane by rotating the porous membrane relative to a detection system, and (c) determining the presence and/or quantity of viable cells captured by the membrane.

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Bath, PA, United States of America

Brian J Kolonia