Howmedica Osteonics Corporation

Revbio, Inc.

Stryker Leibinger Gmbh & Co Kg

Massachusetts Institute of Technology

Evonik Operations Gmbh

Evonik Oil Additives Gmbh

Howmedica Leibinger Inc.

Invivo Therapeutics Corporation

Brian J Hess

Matthew E Murphy

Venkat R Garigapati

George W Kay

Donal O'Mahony

Adrian Sun Wai

Frank-Olaf Maehling

Gerard M Insley

Cassandra L Kimsey

Jon Ahola

Daniel J Siegwart

Liem Vu

Paul Higham

Frank-Olaf Mähling

Joseph P Zitelli

Rene Koschabek

Rhishikesh Gokhale

Ronny Sondjaja

Justin August Langston

Alex Aimetti

Robert Cybert

John Harvey

Cillín P Cleere

Sandra M Murray

Richard L Walker, Jr

Julien Couet

Dennis Thong

Michael G Duckworth

Barbara Voltz

Heng Lian Huang

Frank-Olaf Mahling

Donal O'mahony

Marie A Malitsky

The present disclosure features adhesive compositions and methods of use thereof related to the medical, veterinary, and dental fields.

Compositions and methods for adhesion to surfaces

Provided herein are compositions and their methods of use to adhere (e.g., in wet and dry environments) a variety of materials together.

Embodiments of the disclosure relate to implantable objects and guiding devices, as well as recipient site preparation instruments, bone-implantable materials, and methods of fabrication and use thereof.

Implantable objects, guiding devices, and methods of use thereof

The present application relates to compositions comprising at least one polyalkyl(meth)acrylate polymer, a graft copolymer comprising a copolymer based on ethylene as graft base and one or more polyalkyl(meth)acrylate polymer(s) grafted thereon, and at least one non-grafted ethylene-based copolymer, as well as to the use of such compositions to improve the performance, especially the cold flow properties and injector nozzle coking tendency of middle distillates, especially diesel fuels, biodiesel and blends thereof.

Cold flow improver with broad applicability in mineral diesel, biodiesel and blends thereof

Certain small molecule amino acid phosphate compounds such as phosphoserine and certain multivalent metal compounds such as calcium phosphate containing cements have been found to have improved properties and form an interpenetrating network in the presence of a polymer that contains either an electronegative carbonyl oxygen atom of the ester group or an electronegative nitrogen atom of the amine group as the bonding sites of the polymer surfaces to the available multivalent metal ions.

Organophosphorous, multivalent metal compounds, and polymer adhesive interpenetrating network compositions and methods

A method of synthesizing copolymers is provided. The method can include coupling a degradable polymer to a poly(amino acid) and then deprotecting the copolymer if the poly(amino acid) contains protected side chains. Copolymer compositions are provided. These compositions include PLGA-PLL copolymers, PLGA-PLL-cbz copolymers, and copolymers of a polyester with a carboxylic acid end group coupled to a poly(amino acid) with an amine group. The compositions may include therapeutic blends and formulations of copolymers.

Poly((lactic-co-glycolic acid)-B-lysine) and process for synthesizing a block copolymer of PLGA {poly(lactic-co-glycolic acid)} and PLL (poly-&#x3f5;-cbz-L-lysine)

The present invention relates to a process for preparing grafted polyalkyl(meth)acrylates (PAMAs) containing dispersant repeating units in the polymer backbone as well as in the grafted layer, which polymers are characterized by a low sulfur content, the products available by this process and their use as an additive to fuels, especially to middle distillates and blends thereof. The present invention further relates to a composition comprising the grafted polyalkyl(meth)acrylates prepared by the process according to the present invention and the use of said composition as an additive component to fuels, especially to middle distillates and blends thereof, and for improving the cold flow properties of fuel oil and fuel oil compositions, especially to middle distillate fuels and blends thereof.

Process for preparing low sulfur dispersant polymers

Certain small molecule amino acid phosphate compounds such as phosphoserine and certain multivalent metal compounds such as calcium phosphate containing cements have been found to have improved properties and form an interpenetrating network in the presence of a polymer that contain either an electronegative carbonyl oxygen atom of the ester group or an electronegative nitrogen atom of the amine group as the bonding sites of the polymer surfaces to the available multivalent metal ions.

A stand for use with a syringe is disclosed. The stand includes a base and a clip affixed to the base. The clip engages a portion of the syringe so as to removably secure the syringe to the stand in a position such that the distal end of the syringe is spaced vertically away from the base. Preferably, the syringe includes a handle extending outwardly from a barrel of the syringe, and the feature which the clip engages includes the handle of the syringe.

Syringe and stand

The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.

Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same

A stand for use with a syringe is structured to engage a portion of the syringe in order to maintain the syringe in an upright position. The stand may include an aperture structured to engage the nozzle or the plunger of the syringe. Another embodiment of the stand may include a protrusion structured to engage the proximal end of the syringe, or a clip structured to engage a handle of the syringe. The stand may include a package portion having compartments for holding various components, such as components of a bone cement preparation kit. The proximal and distal portions of the barrel of the syringe may be separable to provide an opening into the barrel through which an injectable material may be inserted. The plunger of the syringe may also include a plunger rod removably affixed to the plunger tip.

Syringe

Growing community of inventors

Charlestown, MA, United States of America

Brian J Hess