3m Innovative Properties Company

Brian J Gabrio

Jimmie Rae Baran, Jr

James S Stefely

Stephen W Stein

Thomas Edward Wood

David J Velasquez

In one aspect, the invention provides a stable dispersion comprising a continuous phase comprising a continuous liquid phase and a plurality of organic nanoparticles; and a dispersed phase comprising particles dispersed in the continuous phase.

Methods of treating mammals with stabilized particle dispersions containing excipient surface-modified nanoparticles

The invention relates to stabilized dispersions containing nanoparticles of use for the administration of medicaments. The dispersions comprise excipient nanoparticles, a dispersed phase comprising medicament and a continuous phase comprising propellant.

Stabilized aerosol dispersions

Stabilized dispersions comprising excipient surface-modified organic nanoparticles and medicament particles

A pressurized metered dose inhaler having an actuator constructed and arranged so as to inhibit airflow due to patient inhalation in the vicinity of the orifice of the nozzle block when the valve stem is in its dispensing position. This design reduces unwanted oropharyngeal deposition of medicament and increases the relative amount of medicament to the lung.

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Oakdale, MN, United States of America

Brian J Gabrio