Medtronic, Inc.

Medtronic Ave, Inc.

Medtronics, Inc.

Other

Vascular Architects, Inc.

Brian J Cox

Jay Alan Lenker

Michael A Evans

Kirsten Freislinger

Thomas J Fogarty

Steven Weinberg

Steven W Kim

Allan R Will

Roman Turovskiy

Darin Charles Gittings

Gholam-Reza Zadno-Azizi

Craig J Coombs

Kirsten F Luehrs

Brian Shiu

Michael B Hayes

Richard O Murphy

Brian A Glynn

Franciscus Laureus Moll

Menno Kalmann

Kenneth Mollenauer

A tubular prosthesis is implanted at a target location within a body lumen by transluminally placing and embedding an expansible prosthesis body within a sealing layer. The sealing layer occludes at least a circumferential band within an interface region between the prosthesis body and the inner wall of the body lumen, thus providing for blockage of body lumen flow past the prosthesis. The sealing layer may be introduced prior to or simultaneously with the prosthesis body. A tubular prosthesis may be implanted in blood vessels, particularly to protect aneurysms.

Methods and apparatus for conformably sealing prostheses within body lumens

The present invention provides controlled expansion endoluminal prostheses and methods for their deployment and expansion. The present stent-grafts generally comprise a radially expansible tubular frame and a plastically expansible liner on the frame. Either the frame or the liner includes a reinforcing element which limits expansion of the stent-graft at a predetermined expanded size. In some embodiments, the reinforcing element restrains the frame, for example, by limiting the circumferential diagonals of perforations on a perforate frame structure. Generally, however, the reinforcing element is included in the liner as circumferentially oriented yarn. A particularly advantageous liner includes composite circumferential yarns having inexpansible fibers wrapped around an expansible fiber, such as a partially oriented yarn, PTFE, or the like.

Cuffed endoluminal prosthesis

Methods and articles for fabricating expansive stents having generally cylindrical configurations with a pattern therein include interconnecting portions from a generally planar sheet of material with a central portion. A pattern is formed in the sheet of material around said central portion corresponding to said pattern having interconnecting portions. The pattern has a generally circular outer margin. The pattern is separated from the sheet of material and causes relative movement between the central portion of the pattern and the outer circular margin in a direction perpendicular to the plane of the central portion. The pattern is transformed from one sheet form into one in cylindrical form to provide an expansible stent having a generally cylindrical configuration.

Method for fabricating a planar eversible lattice which forms a stent when everted

A remote endarterectomy ring stripper (,) includes an elongate shaft (,), having distal (,) and proximal (,) ends, an intima stripping ring (,) mounted to the distal end of the elongate shaft and an intima cutter assembly having an intima cutting element (,), at the stripping ring, operated by a user-operated cutting element actuator (,). Movement of the cutting element severs a length of intima (,), which has been separated from the wall (,) of the blood vessel (,), passing through the stripping ring.

Remote endarterectomy ring stripper

The present invention provides a branching endoluminal prosthesis for use in branching body lumen systems which includes a trunk lumen and first and second branch lumens. The prostheses comprises a radially expandable tubular trunk portion having a prosthetic trunk lumen, and radially expandable tubular first and second branch portions with first and second prosthetic branch lumens, respectively. A radially expandable tubular Y-connector portion provides fluid communication between the prosthetic trunk lumen and the first and second prosthetic branch lumens. Although it is often considered desirable to maximize the column strength of endoluminal prostheses, and although the trunk portion will generally have a larger cross-section than much of the remainder of a branching endoluminal prostheses, the expanded trunk portion is more axially flexible than the expanded Y-connector portion, as insufficient flexibility along the trunk portion may result in leakage between the prosthesis and the trunk lumen of the body lumen system. In contrast, the Y-connector portion benefits form a less axially flexible structure to avoid distortion of the flow balance between the luminal branches.

Endoluminal prostheses and therapies for highly variable body lumens

The present invention provides modular intraluminal tubular prostheses, particularly stents and stent-grafts, for the treatment of disease conditions, particularly aneurysms. Modular sections of the prostheses, or &ldquo;prosthetic modules,&rdquo; may be selectively combined to form a composite prosthesis having characteristics which are tailored to the specific requirements of the patient. Each prosthetic module preferably includes one or more standard interface ends for engaging another module, the module/module interface typically comprising ends which overlap and/or lock within a predetermined axial range. Advantageously, the axial length, cross-section, perimeter, resilient expansive force, axial flexibility, liner permeability, liner extensibility, radial conformability, liner/tubal wall sealing and anchoring, and other prosthetic characteristics may be varied along the axis of the composite prosthesis, and also along the axis of each prosthetic module. The modules are preferably individually introduced into a lumen system of a patient body so that the composite prosthesis is assembled in situ. Ideally, selection of appropriate prosthetic modules and the flexibility of the interface overlap range provides a custom fit intraluminal prosthesis which provides a therapy tailored to the individual patient's needs.

Modular intraluminal prosteheses construction and methods

Limited expansion endoluminal prostheses and methods for their use

The present invention provides modular intraluminal tubular prostheses, particularly stents and stent-grafts, for the treatment of disease conditions, particularly aneurysms. Modular sections of the prostheses, or 'prosthetic modules,' may be selectively combined to form a composite prosthesis having characteristics which are tailored to the specific requirements of the patient. Each prosthetic module preferably includes one or more standard interface ends for engaging another module, the module/module interface typically comprising ends which overlap and/or lock within a predetermined axial range. Advantageously, the axial length, cross-section, perimeter, resilient expansive force, axial flexibility, liner permeability, liner extensibility, radial conformability, liner/tubal wall sealing and anchoring, and other prosthetic characteristics may be varied along the axis of the composite prosthesis, and also along the axis of each prosthetic module. The modules are preferably individually introduced into a lumen system of a patient body so that the composite prosthesis is assembled in situ. Ideally, selection of appropriate prosthetic modules and the flexibility of the interface overlap range provides a custom fit intraluminal prosthesis which provides a therapy tailored to the individual patient's needs.

Stitched stent grafts and methods for their fabrication

Method for deploying cuff prostheses

Methods for the manufacture of radially expansible stents

Modular intraluminal prostheses construction and methods

A device (24) for creating a smooth transition in the intimal lining (18) of a blood vessel (16) during an endarterectomy procedure on a patient (2) includes a delivery catheter (28) insertable into the blood vessel at an opening (8) in the blood vessel. An intimal lining cutter (38, 56) is disposed at the distal end (30) of the catheter. When in proper position, that is where the intimal lining separates from the vessel wall (20), the cutter is actuated to cut the intimal lining without leaving a flap of intimal lining within the blood vessel. The cutter can be of different types, including electrocautery coil (38) or a radially extending cutter blade (56). The invention is typically used with a ring stripper (14) and permits the endarterectomy to be performed using only a single incision into the vessel.

Intimal lining transition device and endarterectomy method

Methods and apparatus for conformably sealing prostheses within body

Growing community of inventors

Los Altos, CA, United States of America

Brian J Cox