Cargill Inc.

Cj Cheiljedang Corporation

Brian J Brazeau

Fernando A Sanchez-Riera

Holly J Jessen

Paula M Hicks

Sara C McFarlan

Mervyn Desouza

So-Young Kim

Steven John Gort

Wei Niu

Young Wook Cho

Kwang Myung Cho

Christopher Solheid

Sherry R Kollmann

Yong-Uk Shin

Jin-Sook Chang

Hyewon Um

Jose Miguel Laplaza

Mervyn L De Souza

David B Weiner

Toby Howard Richardson

David Paul Weiner

Peter Luginbuhl

Lishan Zhao

William Schroeder

Ellen Burke

John Andrew Bohlmann

Tzyy-Jan Han

Shuang Zhou

Jean-Claude De Troostembergh

Willy Obyn

Larry Todd Banner

Paul Loucks

Shannon Nicole Shriver

Sara C Mcfarlan

Sherry R Kollman

Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed.

Compositions and methods of producing methionine

Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and biosynthetic pathways are also useful in the production of R-2-hydroxy-2-(indoly-3-ylmethyl)-4-keto glutaric acid, an intermediate that is formed in certain monatin synthesis pathways, including some biosynthetic pathways.

Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors

Systems and methods for producing levulinic acid from fungal biomass are disclosed. In one implementation, a method for distilling levulinic acid from a glucosamine-containing feedstock is disclosed that yields a relatively pure (e.g., 90% or greater) levulinic acid product from an otherwise problematic waste stream.

Levulinic acid from fungal biomass

A method is disclosed for increasing the specific activity of myo-inositol oxygenase. The method includes incubating a mixture including myo-inositol oxygenase and a non-sulfur containing reductant under conditions effective to increase the specific activity of the myo-inositol oxygenase. Also disclosed are methods for producing D-glucuronic acid and glucurono-&#x3b3;-lactone comprising incubating a mixture including myo-inositol, myo-inositol oxygenase, and oxygen under conditions effective to form 5 grams D-glucuronic acid per liter of the mixture to 400 grams D-glucuronic acid per liter of the mixture. Glucurono-&#x3b3;-lactone can be produced from the D-glucuronic acid product. Also disclosed are organisms and nucleic acids suitable for use in such methods.

Production of glucuronic acid using myo-inositol oxygenase from cryptococcus neoformans

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Excelsior, MN, United States of America

Brian J Brazeau